WNT signalling in the immune system: WNT is spreading its wings (Q37212748)

19 August 2017

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title

WNT signalling in the immune system: WNT is spreading its wings (English)

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19 August 2017

Frank J T Staal

1

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19 August 2017

Tiago C Luis

series ordinal

2

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19 August 2017

Machteld M Tiemessen

series ordinal

3

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19 August 2017

publication date

1 August 2008

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Nature Reviews Immunology

19 August 2017

published in

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19 August 2017

volume

8

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19 August 2017

issue

8

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19 August 2017

page(s)

581-593

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A new nomenclature for int-1 and related genes: the Wnt gene family

19 August 2017

cites work

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Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

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WNT signalling and haematopoiesis: a WNT-WNT situation

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Wnt signalling in stem cells and cancer

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Transcriptional control of t lymphocyte differentiation

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Wnt signaling in the thymus

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Balancing cell adhesion and Wnt signaling, the key role of beta-catenin

31 March 2020

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Wnt/beta-catenin signaling in development and disease

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beta-catenin is a target for the ubiquitin-proteasome pathway

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The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

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SnapShot: Wnt/beta-catenin signaling

31 March 2020

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Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

31 March 2020

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Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin

31 March 2020

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Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.

31 March 2020

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ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

31 March 2020

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Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

31 March 2020

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Noncanonical Wnt signaling promotes apoptosis in thymocyte development

31 March 2020

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SnapShot: Noncanonical Wnt Signaling Pathways

31 March 2020

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Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2.

31 March 2020

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The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

31 March 2020

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Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

31 March 2020

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

31 March 2020

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NFAT signaling in vertebrate development

31 March 2020

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Endothelial cells stimulate T cell NFAT nuclear translocation in the presence of cyclosporin A: involvement of the wnt/glycogen synthase kinase-3 beta pathway

31 March 2020

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Signaling pathways governing stem-cell fate

31 March 2020

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Wnt signaling in the stem cell niche

31 March 2020

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

31 March 2020

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Wnt proteins are lipid-modified and can act as stem cell growth factors

31 March 2020

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Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors

31 March 2020

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Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.

31 March 2020

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Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

31 March 2020

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Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

31 March 2020

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Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation

31 March 2020

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Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

31 March 2020

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Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

31 March 2020

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Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis

31 March 2020

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Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals

31 March 2020

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Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo

31 March 2020

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Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

31 March 2020

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Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

31 March 2020

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T cell development in the adult murine thymus: changes in the expression of the surface antigens Ly2, L3T4 and B2A2 during development from early precursor cells to emigrants

31 March 2020

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New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

31 March 2020

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T-sing progenitors to commit

31 March 2020

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

31 March 2020

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An HMG-box-containing T-cell factor required for thymocyte differentiation.

31 March 2020

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Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

31 March 2020

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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

31 March 2020

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Functional interaction of beta-catenin with the transcription factor LEF-1

31 March 2020

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

31 March 2020

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

31 March 2020

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Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

31 March 2020

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Launching the T-cell-lineage developmental programme

31 March 2020

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Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals

31 March 2020

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The thymus as an inductive site for T lymphopoiesis

31 March 2020

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Zoned out: functional mapping of stromal signaling microenvironments in the thymus

31 March 2020

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Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

31 March 2020

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Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development.

31 March 2020

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beta-Catenin expression enhances generation of mature thymocytes

31 March 2020

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Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

31 March 2020

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Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.

31 March 2020

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Deletion of β-catenin impairs T cell development

31 March 2020

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The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

31 March 2020

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Loss of adenomatous polyposis coli gene function disrupts thymic development

31 March 2020

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Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway

31 March 2020

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Beta-catenin regulates positive selection of thymocytes but not lineage commitment

31 March 2020

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Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection

31 March 2020

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T-cell generation by lymph node resident progenitor cells.

31 March 2020

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Frizzled 9 knock-out mice have abnormal B-cell development

31 March 2020

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Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis

31 March 2020

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Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo

31 March 2020

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Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

31 March 2020

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Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration

31 March 2020

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Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells.

31 March 2020

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The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

31 March 2020

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WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

31 March 2020

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Wnt/beta-catenin signaling in cancer stemness and malignant behavior

31 March 2020

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Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

31 March 2020

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Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis

31 March 2020

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LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

31 March 2020

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

31 March 2020

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Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia

31 March 2020

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Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

31 March 2020

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Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo

31 March 2020

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A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

31 March 2020

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Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

31 March 2020

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Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment.

31 March 2020

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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

31 March 2020

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CBP/p300 are bimodal regulators of Wnt signaling.

31 March 2020

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Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function

31 March 2020

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The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF-beta-catenin-mediated transcription

31 March 2020

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Identification of the haematopoietic stem cell niche and control of the niche size

31 March 2020

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Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

31 March 2020

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Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells

31 March 2020

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

31 March 2020

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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

31 March 2020

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GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen

31 March 2020

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WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells

31 March 2020

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Wnt signaling and phosphorylation status of beta-catenin: importance of the correct antibody tools

31 March 2020

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Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI2360

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19 August 2017

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