Structures of Ebola virus GP and sGP in complex with therapeutic antibodies (Q37213985)

19 August 2017

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies (English)

1 reference

19 August 2017

Orthoebolavirus zairense

0 references

1 reference

Erica Ollmann Saphire

12

Erica Ollmann Saphire

0 references

Christopher A. Cottrell

Christopher A Cottrell

4

0 references

Andrew I. Flyak

Andrew I Flyak

8

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Jesper Pallesen

Jesper Pallesen

1

0 references

James E. Crowe, Jr.

James E Crowe

10

0 references

Marnie L Fusco

7

Marnie L Fusco

1 reference

19 August 2017

11

Kristian G Andersen

1 reference

19 August 2017

5

Kathryn M Hastie

1 reference

19 August 2017

13

Andrew B Ward

1 reference

19 August 2017

6

Hannah L Turner

1 reference

19 August 2017

Charles D Murin

2

1 reference

PMCID

5003320

19 August 2017

Natalia de Val

3

1 reference

PMCID

5003320

19 August 2017

Larry Zeitlin

9

1 reference

19 August 2017

8 August 2016

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19 August 2017

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19 August 2017

1

1 reference

19 August 2017

16128

1 reference

19 August 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/nmicrobiol.2016.128

19 August 2017

0 references

cites work

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Structural and molecular basis for Ebola virus neutralization by protective human antibodies

6 September 2017

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Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

6 September 2017

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Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

6 September 2017

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Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, doub

6 September 2017

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Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies

6 September 2017

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6 September 2017

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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

6 September 2017

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Monitoring of Ebola Virus Makona Evolution through Establishment of Advanced Genomic Capability in Liberia

6 September 2017

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Mechanism of human antibody-mediated neutralization of Marburg virus

6 September 2017

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Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement

6 September 2017

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Structures of protective antibodies reveal sites of vulnerability on Ebola virus

6 September 2017

1 reference

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Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus

6 September 2017

1 reference

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The multiple roles of sGP in Ebola pathogenesis

6 September 2017

1 reference

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Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

6 September 2017

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Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

6 September 2017

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Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

6 September 2017

1 reference

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Type I and type II Fc receptors regulate innate and adaptive immunity

6 September 2017

1 reference

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Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

6 September 2017

1 reference

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Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)

6 September 2017

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

6 September 2017

1 reference

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Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

6 September 2017

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RELION: implementation of a Bayesian approach to cryo-EM structure determination

6 September 2017

1 reference

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Prevention of overfitting in cryo-EM structure determination

6 September 2017

1 reference

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Fabs enable single particle cryoEM studies of small proteins

6 September 2017

1 reference

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Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

A shared structural solution for neutralizing ebolaviruses

6 September 2017

1 reference

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Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change

6 September 2017

1 reference

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Ebolavirus glycoprotein structure and mechanism of entry

6 September 2017

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

6 September 2017

1 reference

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Techniques and tactics used in determining the structure of the trimericebolavirusglycoprotein

6 September 2017

1 reference

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Refinement of protein structures into low-resolution density maps using rosetta

6 September 2017

1 reference

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DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

6 September 2017

1 reference

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Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking

6 September 2017

1 reference

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Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

6 September 2017

1 reference

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Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys

6 September 2017

1 reference

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GlyProt: in silico glycosylation of proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Carbohydrate Structure Suite (CSS): analysis of carbohydrate 3D structures derived from the PDB

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Coot: model-building tools for molecular graphics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Disulfide bond assignment of the Ebola virus secreted glycoprotein SGP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

UCSF Chimera--a visualization system for exploratory research and analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Accurate determination of local defocus and specimen tilt in electron microscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Biochemical analysis of the secreted and virion glycoproteins of Ebola virus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Genomic RNA editing and its impact on Ebola virus adaptation during serial passages in cell culture and infection of guinea pigs.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Epitopes involved in antibody-mediated protection from Ebola virus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

The nonstructural small glycoprotein sGP of Ebola virus is secreted as an antiparallel-orientated homodimer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Privateer: software for the conformational validation of carbohydrate structures.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003320

Comparative Protein Structure Modeling Using MODELLER

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMICROBIOL.2016.128

10.1038/NMICROBIOL.2016.128

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

5003320