B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice (Q37220772)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067092%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice (English)

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26 December 2019

5

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26 December 2019

author name string

Pablo A Silveira

1

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26 December 2019

Joseph Dombrowsky

2

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26 December 2019

Ellis Johnson

3

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26 December 2019

Harold D Chapman

4

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26 December 2019

David V Serreze

6

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26 December 2019

language of work or name

English

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publication date

1 April 2004

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26 December 2019

published in

Journal of Immunology

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26 December 2019

volume

172

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26 December 2019

issue

8

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26 December 2019

page(s)

5086-5094

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B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.

26 December 2019

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Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice

6 September 2017

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B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

6 September 2017

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Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response

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Outer periarteriolar lymphoid sheath arrest and subsequent differentiation of both naive and tolerant immunoglobulin transgenic B cells is determined by B cell receptor occupancy

6 September 2017

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B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

6 September 2017

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B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

6 September 2017

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Receptor editing in self-reactive bone marrow B cells

6 September 2017

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Peripheral deletion of self-reactive B cells

6 September 2017

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6 September 2017

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Genetic control of the immune response to hen's egg-white lysozyme in mice. I. Antibody and T-lymphocyte proliferative responses to the native protein

14 September 2017

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Diagnosis and treatment of pre-insulin dependent diabetes

14 September 2017

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Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

28 September 2017

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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

28 September 2017

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Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.

28 September 2017

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Transitional B cells are the target of negative selection in the B cell compartment

26 June 2018

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Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis

26 June 2018

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Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development

26 June 2018

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BAFF mediates survival of peripheral immature B lymphocytes

3 September 2018

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Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice.

3 September 2018

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B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

3 September 2018

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B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

3 September 2018

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Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

3 September 2018

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Reduced life span of anergic self-reactive B cells in a double-transgenic model

3 September 2018

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3 September 2018

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Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice

3 September 2018

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12 December 2020

The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21

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12 December 2020

Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

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12 December 2020

Development of type 1 diabetes despite severe hereditary B-cell deficiency

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12 December 2020

A defect in central tolerance in NOD mice

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12 December 2020

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

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12 December 2020

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

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12 December 2020

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

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12 December 2020

Multiple H-2 and non-H-2 genes controlling the antilysozyme response: alternative gene constellations can lead to responsiveness

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12 December 2020

Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies

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12 December 2020

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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12 December 2020

Induction of self-tolerance in mature peripheral B lymphocytes

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12 December 2020

Altered Thymic and Peripheral T-Lymphocyte Repertoire Preceding Onset of Diabetes in NOD Mice

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12 December 2020

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice

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12 December 2020

Two mechanisms for the non-MHC-linked resistance to spontaneous autoimmunity

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12 December 2020

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice

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12 December 2020

10.4049/JIMMUNOL.172.8.5086

Identifiers

DOI

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26 December 2019

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26 December 2019

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