8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. (Q37227596)

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29 February 2020

title

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1 (English)

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29 February 2020

2

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Leopoldo Aguilera-aguirre

29 February 2020

3

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29 February 2020

Muralidhar L. Hegde

4

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Zsolt Radak

7

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29 February 2020

Xueqing Ba

8

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9

Istvan Boldogh

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6

Sanjiv Sur

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1

Gyorgy Hajas

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29 February 2020

author name string

K Hazra Tapas

5

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publication date

21 April 2013

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Free Radical Biology and Medicine

29 February 2020

published in

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volume

61

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page(s)

384-394

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Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription

29 February 2020

cites work

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Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine

6 September 2017

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6 September 2017

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8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice

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6 September 2017

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6 September 2017

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Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme

6 September 2017

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Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation

6 September 2017

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Mitochondrial dysfunction increases allergic airway inflammation

6 September 2017

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Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

6 September 2017

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Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects

6 September 2017

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Many faces of Ras activation

6 September 2017

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Increased ROS generation in subsets of OGG1 knockout fibroblast cells

6 September 2017

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Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena

6 September 2017

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6 September 2017

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Regulation of Nox and Duox enzymatic activity and expression

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Choreography of oxidative damage repair in mammalian genomes

6 September 2017

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Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo

6 September 2017

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Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.

6 September 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

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Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

6 September 2017

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The structural basis of the activation of Ras by Sos

6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

28 September 2017

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Features of systemic lupus erythematosus in Dnase1-deficient mice

28 September 2017

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CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

26 June 2018

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Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation

26 June 2018

1 reference

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Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution

3 September 2018

1 reference

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Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis

3 September 2018

1 reference

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Comparative functional analysis of the Rac GTPases

3 September 2018

1 reference

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Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.FREERADBIOMED.2013.04.011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479%20AND%20SRC:MED&resulttype=core&format=json