Unraveling the role of protein dynamics in dihydrofolate reductase catalysis (Q37236476)

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23 February 2020

title

Unraveling the role of protein dynamics in dihydrofolate reductase catalysis (English)

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23 February 2020

1

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23 February 2020

William M Dawson

3

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23 February 2020

Maite Roca

4

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23 February 2020

Edric Joel Loveridge

5

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23 February 2020

Jeremy N. Harvey

7

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23 February 2020

Adrian J Mulholland

8

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23 February 2020

Iñaki Tuñón

9

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23 February 2020

Vicent Moliner

10

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23 February 2020

6

David R Glowacki

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23 February 2020

author name string

J Javier Ruiz-Pernía

2

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23 February 2020

Rudolf K Allemann

11

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23 February 2020

language of work or name

English

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publication date

24 September 2013

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Proceedings of the National Academy of Sciences of the United States of America

23 February 2020

number of pages

6

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based on heuristic

inferred from page(s)

published in

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volume

110

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issue

41

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23 February 2020

page(s)

16344-16349

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Heavy-enzyme kinetic isotope effects on proton transfer in alanine racemase

23 February 2020

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6 September 2017

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6 September 2017

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The dynamic energy landscape of dihydrofolate reductase catalysis

6 September 2017

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Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase

6 September 2017

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Dynamical contributions to enzyme catalysis: critical tests of a popular hypothesis

6 September 2017

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished catalytic performance

3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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Current Status of Transition-State Theory

3 September 2018

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Canonical Variational Theory for Enzyme Kinetics with the Protein Mean Force and Multidimensional Quantum Mechanical Tunneling Dynamics. Theory and Application to Liver Alcohol Dehydrogenase

21 January 2018

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21 January 2018

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Inclusion of quantum-mechanical vibrational energy in reactive potentials of mean force

21 January 2018

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Quantum Dynamics of Hydride Transfer in Enzyme Catalysis

21 January 2018

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A theoretical analysis of rate constants and kinetic isotope effects corresponding to different reactant valleys in lactate dehydrogenase

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24065822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24065822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1312437110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24065822%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24065822%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

24065822

1 reference