Copper oxide nanoparticle toxicity profiling using untargeted metabolomics (Q37243903)

19 August 2017

Copper oxide nanoparticle toxicity profiling using untargeted metabolomics (English)

1 reference

Managing Risks of Nanoparticles

19 August 2017

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Development of reference methods for hazard identification, risk assessment and LCA of engineered nanomaterials

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1 reference

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7

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31 May 2020

Christian G Huber

8

1 reference

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31 May 2020

6

Oliver Kohlbacher

1 reference

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31 May 2020

author name string

Matthew S P Boyles

1

1 reference

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31 May 2020

Christina Ranninger

2

1 reference

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31 May 2020

Roland Reischl

3

1 reference

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31 May 2020

Marc Rurik

4

1 reference

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31 May 2020

Richard Tessadri

5

1 reference

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31 May 2020

publication date

8 September 2016

1 reference

Particle and Fibre Toxicology

19 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27609141%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

13

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31 May 2020

issue

1

1 reference

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31 May 2020

page(s)

49

1 reference

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Approaches to Develop Alternative Testing Strategies to Inform Human Health Risk Assessment of Nanomaterials.

31 May 2020

cites work

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Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline

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6 September 2017

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Comparative proteomic analysis of the molecular responses of mouse macrophages to titanium dioxide and copper oxide nanoparticles unravels some toxic mechanisms for copper oxide nanoparticles in macrophages.

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Toxic mechanisms of copper oxide nanoparticles in epithelial kidney cells.

6 September 2017

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ZnO nanoparticles impose a panmetabolic toxic effect along with strong necrosis, inducing activation of the envelope stress response in Salmonella enterica serovar Enteritidis

6 September 2017

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Occupational exposure to airborne nanomaterials: an assessment of worker exposure to aerosolized metal oxide nanoparticles in semiconductor wastewater treatment

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The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types.

6 September 2017

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Copper: toxicological relevance and mechanisms

6 September 2017

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Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

6 September 2017

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Proposed minimum reporting standards for chemical analysis

6 September 2017

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Measurement of DNA concentration as a normalization strategy for metabolomic data from adherent cell lines

6 September 2017

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Copper oxide nanoparticles induced mitochondria mediated apoptosis in human hepatocarcinoma cells

6 September 2017

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The modality of cell-particle interactions drives the toxicity of nanosized CuO and TiO₂ in human alveolar epithelial cells

6 September 2017

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Selective metabolic effects of gold nanorods on normal and cancer cells and their application in anticancer drug screening

6 September 2017

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Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review.

6 September 2017

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Metabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytes

6 September 2017

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Critical role of surface chemical modifications induced by length shortening on multi-walled carbon nanotubes-induced toxicity

6 September 2017

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Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

6 September 2017

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6 September 2017

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Metabolic profiling reveals disorder of carbohydrate metabolism in mouse fibroblast cells induced by titanium dioxide nanoparticles

6 September 2017

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CuO nanoparticle interaction with human epithelial cells: cellular uptake, location, export, and genotoxicity.

6 September 2017

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Innovation: Metabolomics: the apogee of the omics trilogy

6 September 2017

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Copper: an essential metal in biology

6 September 2017

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Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5)

6 September 2017

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6 September 2017

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Nitric oxide synthases: regulation and function

6 September 2017

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Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity

6 September 2017

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Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

6 September 2017

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Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles

6 September 2017

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Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells

6 September 2017

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Toxicology for the twenty-first century

6 September 2017

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Role of copper transporters in copper homeostasis

6 September 2017

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Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

6 September 2017

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NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells

6 September 2017

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6 September 2017

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1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.

6 September 2017

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The role of the neutral amino acid transporter SNAT2 in cell volume regulation.

6 September 2017

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Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

6 September 2017

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6 September 2017

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A network-based analysis of systemic inflammation in humans

6 September 2017

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Iron and copper metabolism

6 September 2017

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6 September 2017

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Copper toxicity, oxidative stress, and antioxidant nutrients

6 September 2017

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Techniques: Visualizing apoptosis using nuclear magnetic resonance

6 September 2017

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Regulation and measurement of oxidative stress in apoptosis

6 September 2017

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Apoptosis, cell volume regulation and volume-regulatory chloride channels

6 September 2017

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Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress

6 September 2017

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A new mathematical model for relative quantification in real-time RT-PCR

6 September 2017

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Oxygen reduction by nitric-oxide synthases

6 September 2017

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Mechanism of action of camptothecin

6 September 2017

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Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization

6 September 2017

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Accumulation of glycerophosphocholine (GPC) by renal cells: osmotic regulation of GPC:choline phosphodiesterase

6 September 2017

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Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

6 September 2017

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An investigation into the potential for different surface-coated quantum dots to cause oxidative stress and affect macrophage cell signalling in vitro

14 September 2017

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A combined proteomics and metabolomics approach to assess the effects of gold nanoparticles in vitro

14 September 2017

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Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles

14 September 2017

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S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells

14 September 2017

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Surface characteristics, copper release, and toxicity of nano- and micrometer-sized copper and copper(II) oxide particles: a cross-disciplinary study

14 September 2017

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The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists

14 September 2017

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Osmotic regulation of amino acids and system A transport in Madin-Darby canine kidney cells

14 September 2017

1 reference

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Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis virus.

28 September 2017

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Cytotoxicity and genotoxicity of nano - and microparticulate copper oxide: role of solubility and intracellular bioavailability

26 June 2018

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Interference of CuO nanoparticles with metal homeostasis in hepatocytes under sub-toxic conditions

26 June 2018

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Nano-copper induces oxidative stress and apoptosis in kidney via both extrinsic and intrinsic pathways

26 June 2018

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LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells.

26 June 2018

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Insight into the primary mode of action of TiO2 nanoparticles on Escherichia coli in the dark

3 September 2018

1 reference

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Understanding the metabolic fate and assessing the biosafety of MnO nanoparticles by metabonomic analysis.

3 September 2018

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Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions.

3 September 2018

1 reference

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Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.

3 September 2018

1 reference

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Metabonomic studies of biochemical changes in the serum of rats by intratracheally instilled TiO2 nanoparticles.

3 September 2018

1 reference

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Integrated metabonomics analysis of the size-response relationship of silica nanoparticles-induced toxicity in mice

3 September 2018

1 reference

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An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids

3 September 2018

1 reference

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Nanoparticle cytotoxicity depends on intracellular solubility: comparison of stabilized copper metal and degradable copper oxide nanoparticles.

3 September 2018

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NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Activation of nicotinamide N-methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: a rapid in vivo screening method for nanotoxicity

3 September 2018

1 reference

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Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Parenteral glutamine increases serum heat shock protein 70 in critically ill patients

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

NMR-based metabolomics: a powerful approach for characterizing the effects of environmental stressors on organism health.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Early changes in glucose and phospholipid metabolism following apoptosis induction by IFN-gamma/TNF-alpha in HT-29 cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Glutamine induces heat shock protein and protects against endotoxin shock in the rat.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5017021

Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12989-016-0160-6

Global metabolic profiling procedures for urine using UPLC–MS

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12989-016-0160-6

Synthesis and Antibacterial Activity of CuO Nanoparticles Suspension Induced by Laser Ablation in Liquid

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12989-016-0160-6

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

21 January 2018

1 reference

12 December 2020

C/EBP{beta} and its binding element are required for NF{kappa}B-induced COX2 expression following hypertonic stress

1 reference

12 December 2020

Earthworm Sublethal Responses to Titanium Dioxide Nanomaterial in Soil Detected by 1H NMR Metabolomics

1 reference

12 December 2020

Single-walled carbon nanotubes can induce pulmonary injury in mouse model

1 reference

12 December 2020

Apoptosis induced by niacin-related compounds in HL-60 cells

1 reference

12 December 2020

The potential toxicity of copper nanoparticles and copper sulphate on juvenile Epinephelus coioides

1 reference

12 December 2020

Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

1 reference

12 December 2020

Metabolomics reveals the perturbations in the metabolome of Caenorhabditis elegans exposed to titanium dioxide nanoparticles

1 reference

12 December 2020

10.1186/S12989-016-0160-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27609141%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27609141%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

27609141

1 reference