Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice. (Q37248995)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289270%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice (English)

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23 January 2020

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4

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23 January 2020

Juan Carlos Jaume

5

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23 January 2020

author name string

Raya B Elagin

1

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23 January 2020

Sadguna Balijepalli

2

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23 January 2020

Maria J Diacovo

3

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23 January 2020

publication date

16 March 2009

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23 January 2020

published in

Journal of Autoimmunity

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23 January 2020

volume

33

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23 January 2020

issue

1

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23 January 2020

page(s)

50-57

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Insulin stimulates primary beta-cell proliferation via Raf-1 kinase

23 January 2020

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Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

6 September 2017

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An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies

6 September 2017

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IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus

6 September 2017

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Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression

6 September 2017

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Antigen-specific immunotherapy: is it a real possibility to combat T-cell-mediated autoimmunity?

6 September 2017

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Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases

6 September 2017

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Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

6 September 2017

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The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.

6 September 2017

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Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

6 September 2017

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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

6 September 2017

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Cloning and Expression of IDDM-Specific Human Autoantigens

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

6 September 2017

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6 September 2017

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28 September 2017

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Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity

28 September 2017

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28 September 2017

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Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase

26 June 2018

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3 September 2018

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3 September 2018

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3 December 2018

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12 December 2020

64,000 Mr autoantibodies as predictors of insulin-dependent diabetes

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12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

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12 December 2020

Determination of glutamic acid decarboxylase 65 peptides presented by the type I diabetes-associated HLA-DQ8 class II molecule identifies an immunogenic peptide motif

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12 December 2020

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

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12 December 2020

Insulin autoantibodies at the clinical manifestation of type 1 (insulin-dependent) diabetes--a poor predictor of clinical course and antibody response to exogenous insulin

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12 December 2020

Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen

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12 December 2020

Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay

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12 December 2020

Anti-HIV env immunities elicited by nucleic acid vaccines

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12 December 2020

T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice

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12 December 2020

NOD background genes influence T cell responses to GAD 65 in HLA-DQ8 transgenic mice

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12 December 2020

Intradermal delivery of IL-12 naked DNA induces systemic NK cell activation and Th1 response in vivo that is independent of endogenous IL-12 production

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12 December 2020

CXC chemokine ligand 10 neutralization suppresses the occurrence of diabetes in nonobese diabetic mice through enhanced beta cell proliferation without affecting insulitis

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12 December 2020

10.1016/J.JAUT.2009.02.004

Identifiers

DOI

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23 January 2020

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23 January 2020

PubMed publication ID

19289270

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