Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. (Q41756783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10950838%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion (English)

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9 November 2019

9

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9 November 2019

author name string

Y Shi

1

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9 November 2019

J Kanaani

2

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9 November 2019

V Menard-Rose

3

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9 November 2019

Y H Ma

4

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9 November 2019

P Y Chang

5

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9 November 2019

D Hanahan

6

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9 November 2019

A Tobin

7

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9 November 2019

G Grodsky

8

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9 November 2019

publication date

1 September 2000

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American Journal of Physiology - Endocrinology and Metabolism

9 November 2019

published in

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9 November 2019

volume

279

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9 November 2019

issue

3

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9 November 2019

page(s)

E684-94

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Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase

9 November 2019

cites work

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

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Purification and some properties of L-glutamate decarboxylase from human brain

21 January 2018

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Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

21 January 2018

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Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67

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Directed expression of NGF to pancreatic beta cells in transgenic mice leads to selective hyperinnervation of the islets

21 January 2018

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Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene

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Two genes encode distinct glutamate decarboxylases

21 January 2018

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Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat.

21 January 2018

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Glucose modulates gamma-aminobutyric acid release from the pancreatic beta TC6 cell line

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The Influence of γ-Aminobutyric Acid on Hormone Release by the Mouse and Rat Endocrine Pancreas*

21 January 2018

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A threshold distribution hypothesis for packet storage of insulin and its mathematical modeling

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Regional differences in cofactor saturation of glutamate decarboxylase (GAD) in discrete brain nuclei of the rat. Effect of repeated administration of haloperidol on GAD activity in the substantia nigra.

21 January 2018

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The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65.

21 January 2018

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Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

21 January 2018

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Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions.

21 January 2018

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

21 January 2018

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Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

21 January 2018

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Constitutively active stimulatory G-protein alpha s in beta-cells of transgenic mice causes counterregulation of the increased adenosine 3',5'-monophosphate and insulin secretion

21 January 2018

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Differences in insulin secretion between the rat and mouse: role of cAMP.

21 January 2018

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Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

21 January 2018

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Ontogeny and tissue distribution of human GAD expression

21 January 2018

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An update on GABAA receptors

21 January 2018

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Gaba in pancreatic islets: Metabolism and function

21 January 2018

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The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells

21 January 2018

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-Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Is Expressed in Pancreatic Cells and Functions in Insulin but Not -Aminobutyric Acid Secretion

21 January 2018

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Comparison of storage- and signal-limited models of pancreatic insulin secretion.

21 January 2018

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High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma

21 January 2018

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Differential expression of glutamic acid decarboxylase in rat and human islets

21 January 2018

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Gene expression of pancreatic glutamic acid decarboxylase in the nonobese diabetic mouse.

21 January 2018

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21 January 2018

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Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

21 January 2018

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Effect of Muscimol on Glucose-stimulated Somatostatin and Insulin Release from the Isolated, Perfused Rat Pancreas

21 January 2018

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Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

21 January 2018

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Neurotransmitters and their receptors in the islets of Langerhans of the pancreas: what messages do acetylcholine, glutamate, and GABA transmit?

21 January 2018

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Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65

21 January 2018

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21 January 2018

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High Concentration of Gamma-Aminobutyric Acid in Pancreatic Beta Cells

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10950838%20AND%20SRC:MED&resulttype=core&format=json

release_6cvgcer5yrclfmrl2z2fa56gau

9 November 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/6cvgcer5yrclfmrl2z2fa56gau

mapped directly with Wikidata item

24 November 2022

based on heuristic

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