Molecular mechanisms underlying variations in lung function: a systems genetics analysis (Q37252370)

19 August 2017

Molecular mechanisms underlying variations in lung function: a systems genetics analysis (English)

1 reference

19 August 2017

15

1 reference

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3 June 2020

Ozren Polašek

22

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3 June 2020

Marjo-Riitta Järvelin

23

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3 June 2020

Albert V. Smith

31

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3 June 2020

Vilmundur Gudnason

32

1 reference

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3 June 2020

Wim Timens

13

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3 June 2020

Jennie Hui

17

1 reference

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3 June 2020

Debbie Jarvis

25

1 reference

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3 June 2020

Mika Kähönen

26

1 reference

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3 June 2020

Daan Willem Loth

29

1 reference

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3 June 2020

Guy Brusselle

30

1 reference

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3 June 2020

Patricia A. Cassano

36

1 reference

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3 June 2020

Louise Wain

38

1 reference

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3 June 2020

María Soler Artigas

39

1 reference

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3 June 2020

Sina A Gharib

40

1 reference

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3 June 2020

Martin D Tobin

43

1 reference

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3 June 2020

Stephanie J. London

44

1 reference

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3 June 2020

Ian P. Hall

45

1 reference

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3 June 2020

28

Kari E North

1 reference

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3 June 2020

27

Nora Franceschini

1 reference

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3 June 2020

41

David P Strachan

1 reference

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3 June 2020

4

David C Nickle

1 reference

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3 June 2020

16

James F Wilson

1 reference

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3 June 2020

33

Traci M Bartz

1 reference

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3 June 2020

author name string

Ma'en Obeidat

1

1 reference

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3 June 2020

Ke Hao

2

1 reference

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3 June 2020

Yohan Bossé

3

1 reference

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3 June 2020

Yunlong Nie

5

1 reference

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3 June 2020

Michel Laviolette

7

1 reference

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3 June 2020

Andrew J Sandford

8

1 reference

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3 June 2020

Denise D Daley

9

1 reference

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3 June 2020

James C Hogg

10

1 reference

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3 June 2020

W Mark Elliott

11

1 reference

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3 June 2020

Nick Fishbane

12

1 reference

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3 June 2020

Pirro G Hysi

14

1 reference

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3 June 2020

Rajesh Rawal

18

1 reference

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3 June 2020

Holger Schulz

19

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3 June 2020

Beate Stubbe

20

1 reference

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3 June 2020

Jing Hua Zhao

24

1 reference

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3 June 2020

Jemma B Wilk

34

1 reference

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3 June 2020

George T O'Connor

35

1 reference

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3 June 2020

Wenbo Tang

37

1 reference

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3 June 2020

Don D Sin

42

1 reference

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3 June 2020

Peter D Paré

46

1 reference

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3 June 2020

Dirkje S Postma

6

1 reference

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3 June 2020

Caroline Hayward

21

1 reference

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3 June 2020

publication date

21 September 2015

1 reference

The Lancet. Respiratory medicine

19 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

3

1 reference

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3 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

782-795

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json

Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci

3 June 2020

cites work

1 reference

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Bayesian test for colocalisation between pairs of genetic association studies using summary statistics

6 September 2017

1 reference

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Susceptibility to chronic mucus hypersecretion, a genome wide association study

6 September 2017

1 reference

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Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

6 September 2017

1 reference

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Systems genetics approaches to understand complex traits

6 September 2017

1 reference

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A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.

6 September 2017

1 reference

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GSTCD and INTS12 regulation and expression in the human lung

6 September 2017

1 reference

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Systematic identification of trans eQTLs as putative drivers of known disease associations

6 September 2017

1 reference

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Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

6 September 2017

1 reference

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Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls

6 September 2017

1 reference

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Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma.

6 September 2017

1 reference

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Role of D₁/D₂ dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats

6 September 2017

1 reference

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WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

6 September 2017

1 reference

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A statistical framework for joint eQTL analysis in multiple tissues

6 September 2017

1 reference

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Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS

6 September 2017

1 reference

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Lung eQTLs to help reveal the molecular underpinnings of asthma

6 September 2017

1 reference

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Systems genetics in "-omics" era: current and future development

6 September 2017

1 reference

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Systematic localization of common disease-associated variation in regulatory DNA

6 September 2017

1 reference

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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

6 September 2017

1 reference

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Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase

6 September 2017

1 reference

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

6 September 2017

1 reference

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A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

6 September 2017

1 reference

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The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics

6 September 2017

1 reference

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CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

6 September 2017

1 reference

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Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Discovery and preclinical validation of drug indications using compendia of public gene expression data

6 September 2017

1 reference

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Brain expression quantitative trait locus mapping informs genetic studies of psychiatric diseases

6 September 2017

1 reference

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Genetics. Systems genetics.

6 September 2017

1 reference

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Maternal vitamin A supplementation and lung function in offspring

6 September 2017

1 reference

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

6 September 2017

1 reference

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Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

6 September 2017

1 reference

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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

6 September 2017

1 reference

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Genome-wide association study identifies five loci associated with lung function

6 September 2017

1 reference

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Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease

6 September 2017

1 reference

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Common regulatory variation impacts gene expression in a cell type-dependent manner

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Circos: an information aesthetic for comparative genomics

6 September 2017

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Role of HDAC2 in the pathophysiology of COPD.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Mapping the genetic architecture of gene expression in human liver

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Genetics of gene expression and its effect on disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Lung development and susceptibility to chronic obstructive pulmonary disease

6 September 2017

1 reference

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

6 September 2017

1 reference

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Notch in lung development and lung cancer

6 September 2017

1 reference

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The role of transforming growth factor beta in lung development and disease

6 September 2017

1 reference

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Importance of vitamin-A for lung function and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Local anesthetics noncompetitively inhibit function of four distinct nicotinic acetylcholine receptor subtypes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Regulation of retinoic acid signaling during lung morphogenesis

6 September 2017

1 reference

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Sonic hedgehog regulates branching morphogenesis in the mammalian lung

6 September 2017

1 reference

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Inhibition of nonneuronal alpha7-nicotinic receptor for lung cancer treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Identification and characterization of VEGF and FGF from Hydra

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Phenothiazine drug metabolites: dopamine D2 receptor, alpha 1- and alpha 2-adrenoceptor binding

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Association of dopamine-related gene alleles, smoking behavior and decline in FEV1 in subjects with COPD: findings from the lung health study.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Inhibition of histone deacetylase causes emphysema

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Lung development, lung growth and the future of respiratory medicine

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5021067

Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study

3 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Genetic and environmental determinants of level of pulmonary function

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Evidence for major genes influencing pulmonary function in the NHLBI family heart study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Lung development, lung function, and retinoids

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Is COPD in adulthood really so far removed from early development?

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Remodelling of peripheral lung tissue in COPD

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2815%2900380-X

7 January 2021

Vitamin A and lung development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26404118

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/S2213-2600(15)00380-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

26404118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404118%20AND%20SRC:MED&resulttype=core&format=json