MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons (Q37261417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027266%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons (English)

1 reference

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21 February 2020

0 references

0 references

0 references

RB transcriptional corepressor 1

1 reference

negative regulation of apoptotic signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Sabrina Absalon

1

1 reference

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21 February 2020

Venkatesan Raghavan

3

1 reference

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21 February 2020

author name string

Dawn M Kochanek

2

1 reference

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21 February 2020

Anna M Krichevsky

4

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21 February 2020

language of work or name

English

0 references

publication date

1 September 2013

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21 February 2020

published in

Journal of Neuroscience

1 reference

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21 February 2020

volume

33

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21 February 2020

issue

37

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21 February 2020

page(s)

14645-14659

1 reference

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De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

21 February 2020

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The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies

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MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2

6 September 2017

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S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons

6 September 2017

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Pathological implications of cell cycle re-entry in Alzheimer disease

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Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease

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MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons

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Cdk5 nuclear localization is p27-dependent in nerve cells: implications for cell cycle suppression and caspase-3 activation

6 September 2017

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Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

6 September 2017

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Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

6 September 2017

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AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice

6 September 2017

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Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

6 September 2017

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Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

6 September 2017

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

6 September 2017

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Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation

6 September 2017

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Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases.

6 September 2017

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p27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: a proof-of-concept study

6 September 2017

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MicroRNAs in cell proliferation, cell death, and tumorigenesis.

6 September 2017

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Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease

6 September 2017

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The cell cycle as a therapeutic target for Alzheimer's disease

6 September 2017

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Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo.

6 September 2017

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Cell cycle molecules and vertebrate neuron death: E2F at the hub.

6 September 2017

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Cell cycle regulation and neural differentiation

6 September 2017

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Cdk5: One of the links between senile plaques and neurofibrillary tangles?

6 September 2017

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Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

6 September 2017

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6 September 2017

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The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

14 September 2017

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14 September 2017

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The cyclopentenone 15-deoxy-delta(12,14)-prostaglandin J2 inhibits G1/S transition and retinoblastoma protein phosphorylation in immortalized lymphocytes from Alzheimer's disease patients.

14 September 2017

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p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

14 September 2017

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14 September 2017

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Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant

14 September 2017

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Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

28 September 2017

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Cell cycle markers in the hippocampus in Alzheimer's disease.

26 June 2018

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Cyclin E-CDK2 is a regulator of p27Kip1.

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Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death.

26 June 2018

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3 September 2018

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Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not amyloid-beta and tau pathology.

3 September 2018

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Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury.

3 September 2018

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3 September 2018

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Cell cycle activation in postmitotic neurons is essential for DNA repair.

3 September 2018

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3 September 2018

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Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia.

3 September 2018

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3 September 2018

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Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.

3 September 2018

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3 September 2018

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DNA replication precedes neuronal cell death in Alzheimer's disease.

3 September 2018

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3 September 2018

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3 September 2018

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Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

3 September 2018

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Neuronal cell cycle re-entry mediates Alzheimer disease-type changes

3 September 2018

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12 December 2020

Sequential detergent fractionation of primary neurons for proteomics studies

1 reference

12 December 2020

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

1 reference

12 December 2020

Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway

1 reference

12 December 2020

The retinoblastoma protein is essential for survival of postmitotic neurons

1 reference

12 December 2020

The transcription factor E2F1 modulates apoptosis of neurons

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12 December 2020

microRNA detection comes of age

1 reference

12 December 2020

10.1523/JNEUROSCI.1327-13.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027266%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027266%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

24027266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027266%20AND%20SRC:MED&resulttype=core&format=json