Cell cycle molecules and vertebrate neuron death: E2F at the hub. (Q35597038)

9 August 2017

1 reference

title

Cell cycle molecules and vertebrate neuron death: E2F at the hub. (English)

1 reference

9 August 2017

Greene LA

1

1 reference

9 August 2017

Biswas SC

series ordinal

2

1 reference

9 August 2017

Liu DX

series ordinal

3

1 reference

9 August 2017

language of work or name

1 reference

1 January 2004

1 reference

Cell Death & Differentiation

9 August 2017

1 reference

9 August 2017

11

1 reference

9 August 2017

1

1 reference

9 August 2017

49-60

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401341

9 August 2017

0 references

cites work

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

History of the discovery of neuronal death in embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Neuronal cell death, nerve growth factor and neurotrophic models: 50 years on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Regulation of cell survival by secreted proneurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

c-Jun and the transcriptional control of neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Neuronal life and death: an essential role for the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cell death and the cell cycle: a relationship between transformation and neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The molecular mechanisms of neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cyclins and cyclin-dependent kinases: a biochemical view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Alterations in cell cycle regulation underlie cisplatin induced apoptosis of dorsal root ganglion neurons in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

c-Jun and cyclin D1 proteins as mediators of neuronal death after a focal ischaemic insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cyclin-dependent kinases as a therapeutic target for stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cell cycle markers in the hippocampus in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The cell division cycle and the pathophysiology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cdk5 behind the wheel: a role in trafficking and transport?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Review of flavopiridol, a cyclin-dependent kinase inhibitor, as breast cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The mechanism of Ara-C-induced apoptosis of differentiating cerebellar granule neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

CDK inhibitors in clinical development for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The transcription factor E2F-1 in SV40 T antigen-induced cerebellar Purkinje cell degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Differential effects of cyclin-dependent kinase blockers upon cell death in the developing retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Transient hypoxia may lead to neuronal proliferation in the developing mammalian brain: from apoptosis to cell cycle completion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

A revised picture of the E2F transcriptional network and RB function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Altered distribution of cell cycle transcriptional regulators during Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The Rb pathway in neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The retinoblastoma gene family is differentially expressed during embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Expression of the E2F and retinoblastoma families of proteins during neural differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The transcription factor E2F1 promotes dopamine-evoked neuronal apoptosis by a mechanism independent of transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Increased expression of the transcription factor E2F1 during dopamine-evoked, caspase-3-mediated apoptosis in rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Up-regulation of E2F-1 in Down's syndrome brain exhibiting neuropathological features of Alzheimer-type dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Attenuation of neurotoxicity in cortical cultures and hippocampal slices from E2F1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

The myb gene family in cell growth, differentiation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

A B-myb promoter corepressor site facilitates in vivo occupation of the adjacent E2F site by p107 x E2F and p130 x E2F complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

E2F4 actively promotes the initiation and maintenance of nerve growth factor-induced cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Alzheimer's disease research enters a "new cycle": how significant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Neuronal apoptosis at the G1/S cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Cyclin-dependent kinases as potential targets to improve stroke outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Small molecules as inhibitors of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

Men are but worms: neuronal cell death in C elegans and vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Signal transduction in neuronal death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cell cycle and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

In vivo viability of postmitotic Purkinje neurons requires pRb family member function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Kainate-induced apoptosis in cultured murine cerebellar granule cells elevates expression of the cell cycle gene cyclin D1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Gene profiling in spinal cord injury shows role of cell cycle in neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cyclin D1 and Cdk4 protein induction in motor neurons after transient spinal cord ischemia in rabbits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Two waves of cyclin B and proliferating cell nuclear antigen expression during dopamine-triggered neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Induction of mitosis-related genes during dopamine-triggered apoptosis in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Activated mitogenic signaling induces a process of dedifferentiation in Alzheimer's disease that eventually results in cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Regulation of the retinoblastoma-dependent Mdm2 and E2F-1 signaling pathways during neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401341

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401341

1 reference

Dimensions Publication ID

9 August 2017

1006719562

0 references

Fatcat ID

release_b45bgazgk5adnpuava64bsy7we

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/b45bgazgk5adnpuava64bsy7we

24 November 2022

mapped directly with Wikidata item

1 reference