Mutations of the ompK36 porin gene and promoter impact responses of sequence type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin. (Q37263324)

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scientific article published on 12 August 2013

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English	Mutations of the ompK36 porin gene and promoter impact responses of sequence type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin.	scientific article published on 12 August 2013

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7 March 2020

Mutations of the ompK36 porin gene and promoter impact responses of sequence type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin (English)

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7 March 2020

Klebsiella pneumoniae

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Barry N Kreiswirth

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David S Perlin

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Liang Chen

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Jae H Hong

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Shaoji Cheng

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Binghua Hao

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Ryan K Shields

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Annie N Farrell

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Yanan Zhao

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M Hong Nguyen

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7 March 2020

Antimicrobial Agents and Chemotherapy

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7 March 2020

5258-5265

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7 March 2020

Epidemiology and molecular characterization of bacteremia due to carbapenem-resistant Klebsiella pneumoniae in transplant recipients

1 reference

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6 September 2017

Characterization of porin expression in Klebsiella pneumoniae Carbapenemase (KPC)-producing K. pneumoniae identifies isolates most susceptible to the combination of colistin and carbapenems.

1 reference

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6 September 2017

The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic/pharmacodynamic model

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6 September 2017

The combination of doripenem and colistin is bactericidal and synergistic against colistin-resistant, carbapenemase-producing Klebsiella pneumoniae

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6 September 2017

Treatment outcome of bacteremia due to KPC-producing Klebsiella pneumoniae: superiority of combination antimicrobial regimens

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6 September 2017

Klebsiella pneumoniae ST258 producing KPC-3 identified in italy carries novel plasmids and OmpK36/OmpK35 porin variants

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6 September 2017

Global spread of Carbapenemase-producing Enterobacteriaceae

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6 September 2017

Synergistic killing of multidrug-resistant Pseudomonas aeruginosa at multiple inocula by colistin combined with doripenem in an in vitro pharmacokinetic/pharmacodynamic model

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6 September 2017

Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention

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6 September 2017

Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence

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6 September 2017

Multiplex real-time PCR assay for detection and classification of Klebsiella pneumoniae carbapenemase gene (bla KPC) variants

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6 September 2017

Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene

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6 September 2017

Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae

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6 September 2017

Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection

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6 September 2017

Risk factors and clinical impact of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.

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6 September 2017

Attributable mortality rate for carbapenem-resistant Klebsiella pneumoniae bacteremia

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6 September 2017

Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae

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6 September 2017

The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria

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Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

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Isolation of imipenem-resistant Enterobacter species: emergence of KPC-2 carbapenemase, molecular characterization, epidemiology, and outcomes

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Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium

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Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance.

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6 September 2017

Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes

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6 September 2017

A porin from Klebsiella pneumoniae: sequence homology, three-dimensional model, and complement binding

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6 September 2017

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14 September 2017

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26 June 2018

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12 December 2020

based on heuristic

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Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment

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https://pubmed.ncbi.nlm.nih.gov/23939888

12 December 2020

based on heuristic

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Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Importance of Combination Therapy

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https://pubmed.ncbi.nlm.nih.gov/23939888

12 December 2020

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