Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling (Q37270647)

19 August 2017

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling (English)

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19 August 2017

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Robert S. Langer, Jr.

13

Robert Langer

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19 August 2017

1

Gaurav Sahay

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Christopher A Alabi

3

Christopher Alabi

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Emmanouil D. Karagiannis

Emmanouil Karagiannis

7

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Avi Schroeder

Avi Schroeder

12

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Sovan Sarkar

Sovan Sarkar

5

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William Querbes

2

William Querbes

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author name string

Ahmed Eltoukhy

4

1 reference

19 August 2017

Christopher Zurenko

6

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19 August 2017

Kevin Love

8

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19 August 2017

Delai Chen

9

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19 August 2017

Roberto Zoncu

10

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19 August 2017

Yosef Buganim

11

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19 August 2017

Daniel G Anderson

14

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19 August 2017

23 June 2013

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19 August 2017

6

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based on heuristic

inferred from page(s)

published in

Nature Biotechnology

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19 August 2017

31

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19 August 2017

7

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19 August 2017

653-658

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https://scigraph.springernature.com/pub.10.1038/nbt.2614

19 August 2017

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cites work

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Nucleic acid delivery: the missing pieces of the puzzle?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Therapeutic siRNA silencing in inflammatory monocytes in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Complex inhibitory effects of nitric oxide on autophagy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

More effective nanomedicines through particle design

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Regulation of mammalian autophagy in physiology and pathophysiology.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Endocytosis of nanomedicines.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Lipid-like materials for low-dose, in vivo gene silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Rab27a and Rab27b control different steps of the exosome secretion pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Silencing by small RNAs is linked to endosomal trafficking

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Mechanisms of endocytosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Knocking down barriers: advances in siRNA delivery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Cellular cholesterol trafficking and compartmentalization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Characterization of the intracellular dynamics of a non-degradative pathway accessed by polymer nanoparticles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Modulation of cellular cholesterol transport and homeostasis by Rab11.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Concanamycin A, the specific inhibitor of V-ATPases, binds to the V(o) subunit c.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

6 September 2017

The Rab GTPase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Effect of bafilomycin A1 and nocodazole on endocytic transport in HeLa cells: implications for viral uncoating and infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Endocytic trafficking of sphingomyelin depends on its acyl chain length

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Systems survey of endocytosis by multiparametric image analysis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

RISC hitches onto endosome trafficking.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814166

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.2614

Cytoscape: a software environment for integrated models of biomolecular interaction networks

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.2614

BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.2614

Proof of concept for next-generation nanoparticle drugs in humans

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23792629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23792629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.2614

1 reference

Dimensions Publication ID

19 August 2017

0 references

1 reference

19 August 2017

1 reference