Current insights on the biology and clinical aspects of VEGF regulation (Q37272329)

19 August 2017

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title

Current insights on the biology and clinical aspects of VEGF regulation (English)

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19 August 2017

Daniel M Birk

1

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19 August 2017

Joel Barbato

series ordinal

2

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19 August 2017

Leila Mureebe

series ordinal

3

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19 August 2017

Rabih A Chaer

series ordinal

4

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19 August 2017

publication date

17 September 2008

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Vascular and Endovascular Surgery

19 August 2017

published in

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19 August 2017

volume

42

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19 August 2017

issue

6

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19 August 2017

page(s)

517-530

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Molecular control of lymphangiogenesis

19 August 2017

cites work

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Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis

21 January 2018

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VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression.

21 January 2018

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VEGF as a mediator of tumor-associated immunodeficiency

21 January 2018

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Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

21 January 2018

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Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?

21 January 2018

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Leptin and pubertal development

21 January 2018

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Transcriptional regulation of vascular endothelial growth factor in cancer.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

VEGF inhibitors in cancer therapy

21 January 2018

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Vascular endothelial growth factor: basic science and clinical progress

21 January 2018

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Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

21 January 2018

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Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200

21 January 2018

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Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application

21 January 2018

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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

21 January 2018

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Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Regression of established tumors and metastases by potent vascular endothelial growth factor blockade

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

A reassessment of vascular endothelial growth factor in central nervous system pathology

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

21 January 2018

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https://api.crossref.org/works/10.1177%2F1538574408322755

Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Angiogenesis, vascular endothelial growth factor and platelet-derived growth factor-BB expression, iron deposition, and oxidation-specific epitopes in stented human coronary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermitt

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

VEGF polymorphisms and severity of atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Adventitial VEGF165 gene transfer prevents lumen loss through induction of positive arterial remodeling after PTCA in porcine coronary arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Myocardial Doppler tissue velocity improves following myocardial gene therapy with VEGF-A165 plasmid in patients with inoperable angina pectoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor is a secreted angiogenic mitogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 and 14q24-q31 regions, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Novel human vascular endothelial growth factor genes VEGF-B and VEGF-C localize to chromosomes 11q13 and 4q34, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Molecular cloning of a novel vascular endothelial growth factor, VEGF-D

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Placenta growth factor: identification and characterization of a novel isoform generated by RNA alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

The role of tumor lymphangiogenesis in metastatic spread.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

A model for gene therapy of human hereditary lymphedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Constitutive and inducible expression and regulation of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Modulation of VEGF production by pH and glucose in retinal Müller cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Expression of the vascular endothelial growth factor gene is inhibited by p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Oncogenes as inducers of tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Signaling angiogenesis via p42/p44 MAP kinase and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Protein kinase C inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

AP-1 function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

AP-1: linking hydrogen peroxide and oxidative stress to the control of cell proliferation and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Smad4 transcriptional pathways and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Increased MAPK expression and activity in primary human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Different regulation of vascular endothelial growth factor expression by the ERK and p38 kinase pathways in v-ras, v-raf, and v-myc transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Prolactin-induced expression of vascular endothelial growth factor via Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Ultraviolet-A-induced transactivation of the vascular endothelial growth factor gene in HaCaT keratinocytes is conveyed by activator protein-2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Retinoic acid induces VEGF gene expression in human retinal pigment epithelial cells (ARPE-19).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Prostaglandins up-regulate vascular endothelial growth factor production through distinct pathways in differentiated U937 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

The influence of biomechanical parameters on the expression of VEGF and endostatin in the bone and joint system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1538574408322755

21 January 2018

Identifiers

DOI

10.1177/1538574408322755

1 reference

19 August 2017

1 reference