A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth (Q37281454)

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scientific article published on 23 June 2009

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English	A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth	scientific article published on 23 June 2009

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A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth (English)

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Masashi Idogawa

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Hiromu Suzuki

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Kohzoh Imai

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Yasuhisa Shinomura

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Yasuhisa Shinomura

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Minoru Toyota

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Reo Maruyama

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Hiroaki Mita

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Fumio Aoki

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Hirofumi Akashi

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Lisa Kashima

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Kazuyoshi Yanagihara

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Masahiro Fujita

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Masao Hosokawa

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Masanobu Kusano

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Sorin Vasile Sabau

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Haruyuki Tatsumi

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Takashi Tokino

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23 June 2009

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198

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1 February 2020

https://scigraph.springernature.com/pub.10.1186/1471-2407-9-198

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Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

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KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

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Differences in the histological findings, phenotypic marker expressions and genetic alterations between adenocarcinoma of the gastric cardia and distal stomach

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ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation

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12 December 2020

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inferred from PubMed ID database lookup

Activation of c-K-ras mutations in human gastrointestinal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19545448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/19545448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-9-198

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1 February 2020

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1 February 2020

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