Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression (Q37297734)

19 August 2017

Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression (English)

1 reference

19 August 2017

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1 reference

Fang Wang

1

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19 August 2017

Jian Xu

2

1 reference

19 August 2017

Quan Zhu

3

1 reference

19 August 2017

Xuejun Qin

4

1 reference

19 August 2017

Yan Cao

5

1 reference

19 August 2017

Jiangfang Lou

6

1 reference

19 August 2017

Yuqiao Xu

7

1 reference

19 August 2017

Xing Ke

8

1 reference

19 August 2017

Qing Li

9

1 reference

19 August 2017

Erfu Xie

10

1 reference

19 August 2017

Lixia Zhang

11

1 reference

19 August 2017

Ruihong Sun

12

1 reference

19 August 2017

Liang Chen

13

1 reference

19 August 2017

Bingliang Fang

14

1 reference

19 August 2017

Shiyang Pan

15

1 reference

19 August 2017

language of work or name

English

0 references

publication date

11 November 2013

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19 August 2017

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19 August 2017

8

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19 August 2017

11

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19 August 2017

e79064

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Creative Commons Attribution 4.0 International

19 August 2017

start time

11 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Coordinated changes in DNA methylation in antigen-specific memory CD4 T cells

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Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation

6 September 2017

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The multi-functional roles of GNMT in toxicology and cancer

6 September 2017

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Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

6 September 2017

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DNA methylation inhibitors in cancer: recent and future approaches

6 September 2017

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DNA methylation and microRNA dysregulation in cancer

6 September 2017

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Gene silencing of Toll-like receptor 2 inhibits proliferation of human liver cancer cells and secretion of inflammatory cytokines

6 September 2017

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Increased DNA methyltransferase activity and DNA methylation following Epidermal Growth Factor stimulation in ovarian cancer cells

6 September 2017

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DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo

6 September 2017

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Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

6 September 2017

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Targeting epigenetic networks with polypharmacology: a new avenue to tackle cancer

6 September 2017

1 reference

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IFN-γ, IL-17 and TGF-β involvement in shaping the tumor microenvironment: The significance of modulating such cytokines in treating malignant solid tumors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

6 September 2017

1 reference

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Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans

6 September 2017

1 reference

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DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.

6 September 2017

1 reference

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The two faces of interferon-γ in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

6 September 2017

Cancer statistics, 2010

1 reference

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Tumour escape mechanisms and their therapeutic implications in combination tumour therapy

6 September 2017

1 reference

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Clinical Use of Interferon-gamma

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

6 September 2017

1 reference

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Cancer immunoediting and "spontaneous" tumor regression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Distinct Methylation of IFNG in the Gut

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Interferons, immunity and cancer immunoediting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Molecular enzymology of mammalian DNA methyltransferases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

DNA methylation and the expanding epigenetics of T cell lineage commitment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Methylation and demethylation in the regulation of genes, cells, and responses in the immune system

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

The property of methylated APC gene promotor and its influence on lung cancer cell line

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

CpG methylation of the IFNG gene as a mechanism to induce immunosuppression [correction of immunosupression] in tumor-infiltrating lymphocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

CpG methylation patterns in the IFNgamma promoter in naive T cells: variations during Th1 and Th2 differentiation and between atopics and non-atopics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Enhanced tumorigenesis in HTLV-1 tax-transgenic mice deficient in interferon-gamma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Human Th1 and Th17 cells exhibit epigenetic stability at signature cytokine and transcription factor loci

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Maintenance of DNA methylation: Dnmt3b joins the dance.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Enhanced demethylation of interferon-γ gene promoter in peripheral blood mononuclear cells is associated with acute-on-chronic hepatitis B liver failure.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Early epigenetic events regulate the adaptive immune response gene CIITA.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Cytosine methylation profiles as a molecular marker in non-small cell lung cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Effect of promoter methylation on the regulation of IFN-gamma gene during in vitro differentiation of human peripheral blood T cells into a Th2 population

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823966

Cytokine levels (IL-6 and IFN-gamma), acute phase response and nutritional status as prognostic factors in lung cancer

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24244422

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24244422

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24244422

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0079064

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

24244422

1 reference