Lysosomal membrane permeabilization in cell death (Q37310191)

19 August 2017

1 reference

title

Lysosomal membrane permeabilization in cell death (English)

1 reference

19 August 2017

1 reference

2

G Kroemer

0 references

Patricia Boya

object named as

P Boya

series ordinal

1

0 references

language of work or name

English

0 references

publication date

1 October 2008

1 reference

19 August 2017

1 reference

19 August 2017

27

1 reference

19 August 2017

50

1 reference

19 August 2017

6434-6451

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2008.310

19 August 2017

0 references

cites work

Necrosis and the serpin under't

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The human brm protein is cleaved during apoptosis: the role of cathepsin G

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cell death in early neural life

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Inhibition of macroautophagy triggers apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Viral proteins targeting mitochondria: controlling cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cell death independent of caspases: a review.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin L plays an active role in involution of the mouse mammary gland

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-m

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Developmental cell death: morphological diversity and multiple mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Commentary. Lysosomotropic agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Molecular bases of cellular iron toxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Sensitization to the lysosomal cell death pathway upon immortalization and transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomes as targets for cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Bax inhibition protects against free fatty acid-induced lysosomal permeabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Organelle-specific initiation of cell death pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cell death modalities: classification and pathophysiological implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Extracellular acidification alters lysosomal trafficking in human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cell death by necrosis: towards a molecular definition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Functional role of aspartic proteinase cathepsin D in insect metamorphosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

31 March 2020

Lysosomes in cell death

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Silica binding and toxicity in alveolar macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Participation of a cathepsin L-type protease in the activation of caspase-3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal membrane permeabilization during apoptosis--involvement of Bax?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Simultaneous human papilloma virus type 16 E7 and cdk inhibitor p21 expression induces apoptosis and cathepsin B activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Autophagy: from phenomenology to molecular understanding in less than a decade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

p38 MAPK plays an essential role in apoptosis induced by photoactivation of a novel ethylene glycol porphyrin derivative

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Mitochondrial membrane permeabilization in cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomes and autophagy in cell death control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

BID-deficient breast cancer MCF-7 cells as a model for the study of autophagy in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

An overview of the serpin superfamily

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Steroid regulation of midgut cell death during Drosophila development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Autophagy in the Pathogenesis of Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Engulfment is required for cell competition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Induction of cell death by the lysosomotropic detergent MSDH.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal cysteine proteases in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Serine protease inhibitor 2A is a protective factor for memory T cell development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

NF-kappaB protects from the lysosomal pathway of cell death.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Serine protease inhibitor 2A inhibits caspase-independent cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Emerging roles of proteases in tumour suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomes: fusion and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Self-eating and self-killing: crosstalk between autophagy and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

S-Nitrosylation of mitochondrial caspases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

p53 has a direct apoptogenic role at the mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cell killing by lysosomotropic detergents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Autophagy: process and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Apoptosis-inducing factor: vital and lethal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Signaling pathways in cell death and survival after photodynamic therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cysteine cathepsin proteases as pharmacological targets in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Caspase- and mitochondrial dysfunction-dependent mechanisms of lysosomal leakage and cathepsin B activation in DNA damage-induced apoptosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The cysteine protease inhibitors cystatins inhibit herpes simplex virus type 1-induced apoptosis and virus yield in HEp-2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The apoptosome: signalling platform of cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The combination of bcl-2 expression and NGF-deprivation facilitates the selective destruction of BAD protein in living sympathetic neurons.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Imaging proteolysis by living human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Apoptosis: controlled demolition at the cellular level

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

31 March 2020

Lysosomal labilization

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Protease signalling in cell death: caspases versus cysteine cathepsins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal cysteine proteases: facts and opportunities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Mechanism of apoptosis induced by a lysosomotropic agent, L-Leucyl-L-Leucine methyl ester

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The function of apolipoproteins L.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Analysis of the lysosomal storage disease Chediak-Higashi syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal and mitochondrial pathways in H2O2-induced apoptosis of alveolar type II cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

The BCL-2 protein family: opposing activities that mediate cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal destabilization in p53-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Bid acts on the permeability transition pore complex to induce apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Delayed oxidant-induced cell death involves activation of phospholipase A2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Lysosomal cathepsins in embryonic programmed cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

Cathepsin D gene expression outlines the areas of physiological cell death during embryonic development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.310

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.310

1 reference

19 August 2017

1 reference

PubMed ID

18955971