Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis (Q37310806)

19 August 2017

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title

Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis (English)

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19 August 2017

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Edward Rubenstein

1

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19 August 2017

1 November 2008

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Journal of Neuropathology & Experimental Neurology

19 August 2017

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19 August 2017

67

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19 August 2017

11

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19 August 2017

1035-1040

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Biologic effects of and clinical disorders caused by nonprotein amino acids

19 August 2017

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An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides

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Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam

21 January 2018

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Azetidine-2-carboxylic acid in garden beets (Beta vulgaris).

21 January 2018

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Influence of proline residues on protein conformation

21 January 2018

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Woes of proline: a cautionary kinetic tale

21 January 2018

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Synthesis and peptide bond orientation in tetrapeptides containing L-azetidine-2-carboxylic acid and L-proline

21 January 2018

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Azetidine-derived amino acids versus proline derivatives. alternative trends in reverse turn induction

21 January 2018

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Azetidine-2-carboxylic acid: a new cyclic imino acid occurring in plants

21 January 2018

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Myelin basic protein: a multifunctional protein

21 January 2018

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An immunodominant epitope of myelin basic protein is an amphipathic alpha-helix

21 January 2018

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Purification of immunologically active recombinant 21.5 kDa isoform of human myelin basic protein.

21 January 2018

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Amino acid sequence of the encephalitogenic basic protein from human myelin

21 January 2018

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B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

21 January 2018

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Effect of phosphorylation of myelin basic protein by MAPK on its interactions with actin and actin binding to a lipid membrane in vitro

21 January 2018

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Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope

21 January 2018

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Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS.

21 January 2018

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Neurofascin as a novel target for autoantibody-mediated axonal injury

21 January 2018

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Neurofascin assembles a specialized extracellular matrix at the axon initial segment

21 January 2018

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Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis.

21 January 2018

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Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis.

21 January 2018

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Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms

21 January 2018

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Glial regulation of the axonal membrane at nodes of Ranvier

21 January 2018

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betaIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG.

21 January 2018

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Kinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation

21 January 2018

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A combined NMR and molecular dynamics simulation study to determine the conformational properties of agonists and antagonists against experimental autoimmune encephalomyelitis.

21 January 2018

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Risk alleles for multiple sclerosis identified by a genomewide study

21 January 2018

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Age at onset of multiple sclerosis may be influenced by place of residence during childhood rather than ancestry

21 January 2018

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Multiple sclerosis prevalence among Sardinians: further evidence against the latitude gradient theory

21 January 2018

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Multiple sclerosis in the Faroe Islands: an epitome

21 January 2018

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Regional variation of multiple sclerosis prevalence in Canada

21 January 2018

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The prevalence and clinical characteristics of MS in northern Japan.

21 January 2018

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The emergence of multiple sclerosis, 1870-1950: a puzzle of historical epidemiology

21 January 2018

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Role of return migration in the emergence of multiple sclerosis in the French West Indies

21 January 2018

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Structural changes of the central nervous system in swayback (Enzootic Ataxia) of lambs. V. Electron microscopic observations of the corpus callosum.

21 January 2018

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Multiple sclerosis and the swayback story

21 January 2018

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California Goats with a Disease Resembling Enzootic Ataxia or Swayback

21 January 2018

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A progressive spinal myelinopathy in beef cattle.

21 January 2018

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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

21 January 2018

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Opening the pore hinges on proline

21 January 2018

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A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics.

21 January 2018

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Oxygen sensing by HIF hydroxylases

21 January 2018

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Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for

21 January 2018

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Crystal and molecular structure of a collagen-like polypeptide (Pro-Pro-Gly)10

21 January 2018

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Extracellular matrix synthesis is required for the movement of sclerotome and neural crest cells on collagen

21 January 2018

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Neural crest migration in 3D extracellular matrix utilizes laminin, fibronectin, or collagen

21 January 2018

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Neural crest cell migratory pathways in the trunk of the chick embryo

21 January 2018

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Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution.

21 January 2018

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10.1097/NEN.0B013E31818ADD4A

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18957898