Hallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines (Q37315499)

19 August 2017

Hallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines (English)

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lysergic acid diethylamide

19 August 2017

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J C Winter

1

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19 August 2017

1 November 2008

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19 August 2017

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19 August 2017

203

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19 August 2017

2

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19 August 2017

251-263

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https://scigraph.springernature.com/pub.10.1007/s00213-008-1356-8

19 August 2017

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cites work

PCP and hallucinogens

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https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

A Clinical Plan for MDMA (Ecstasy) in the Treatment of Posttraumatic Stress Disorder (PTSD): Partnering with the FDA

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

A Controlled Comparison of Lysergic Acid Diethylamide (LSD) and Dextroamphetamine in Alcoholics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Discriminative stimulus effects of ethanol in mice lacking the gamma-aminobutyric acid type A receptor delta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Human hallucinogenic drug research in the United States: a present-day case history and review of the process

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Psychological and cardiovascular effects and short-term sequelae of MDMA ("ecstasy") in MDMA-naïve healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00213-008-1356-8

Evidence of catecholamine mediation in the "aberrant" behaviour induced by lysergic acid diethylamide (LSD) in the rat.

21 January 2018

1 reference

12 December 2020

Research on psychedelics moves into the mainstream

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12 December 2020

A possible correlation between drug-induced hallucinations in man and a behavioural response in mice

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12 December 2020

Comparison of psilocin with psilocybin, mescaline and LSD-25

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12 December 2020

Serotonergic receptor subtypes and hallucinogen-induced stimulus control

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12 December 2020

The action of tryptamine on the dog spinal cord and its relationship to the agonistic actions of LSD-like psychotogens

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12 December 2020

Involvement of 5-HT receptor subtypes in the discriminative stimulus properties of mescaline

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12 December 2020

Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents

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12 December 2020

SEROTONIN-LSD INTERACTIONS

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12 December 2020

Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI

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12 December 2020

Locomotor and discriminative-stimulus effects of cocaine in dopamine D5 receptor knockout mice

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12 December 2020

Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5-HT2- versus 5-HT1C-selective antagonist

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12 December 2020

Cross tolerance between mescaline and LSD-25 with a comparison of the mescaline and LSD reactions

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12 December 2020

Blockade of the stimulus properties of mescaline by a serotonin antagonist

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12 December 2020

The dopamine receptor: Differential binding of d-LSD and related agents to agonist and antagonist states

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12 December 2020

[Dimethyltryptamine: a new psycho-active drug.]

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12 December 2020

2,5-Dimethoxy-4-methylamphetamine: new hallucinogenic drug.

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12 December 2020

Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.

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12 December 2020

Discriminative stimulus and subjective effects of opioids with mu and kappa activity: data from laboratory animals and human subjects

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12 December 2020

Effects of mescaline and lysergic acid (d-LSD-25)

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12 December 2020

The 5-HT1A receptor and the stimulus effects of LSD in the rat.

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12 December 2020

Antagonism of the effects of the hallucinogen DOM and the purported 5-HT agonist quipazine by 5-HT2 antagonists

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12 December 2020

Cross tolerance between LSD and psilocybin

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12 December 2020

The discriminative stimulus properties of 2,5-dimethoxy-4-methylamphetamine (DOM): differentiation from amphetamine

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12 December 2020

A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS.

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12 December 2020

Serotonin receptor subtype mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine

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12 December 2020

Effects of novel antipsychotics with mixed D(2) antagonist/5-HT(1A) agonist properties on PCP-induced social interaction deficits in the rat.

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12 December 2020

Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD

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12 December 2020

Effects of (--)delta-9-trans-tetrahydrocannabinol in man

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12 December 2020

Molecular biology of 5-HT receptors

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12 December 2020

Screening hallucinogenic drugs: systematic study of three behavioral tests

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12 December 2020

Dimethyltryptamin: its metabolism in man; the relation to its psychotic effect to the serotonin metabolism

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12 December 2020

Psychotomimetic drugs; chemical and pharmacological aspects

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12 December 2020

Serotonin and Hallucinogens

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12 December 2020

The stimulus properties of LSD in C57BL/6 mice

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12 December 2020

Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta-chlorophenylpiperazine and placebo

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12 December 2020

Role of serotonergic 5-HT2A receptors in the psychotomimetic actions of phencyclidine

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12 December 2020

Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats

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12 December 2020

Nisoxetine and amphetamine share discriminative stimulus properties in mice

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12 December 2020

Serotonergic/glutamatergic interactions: the effects of mGlu 2/3 receptor ligands in rats trained with LSD and PCP as discriminative stimuli

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12 December 2020

Phenoxybenzamine antagonism of tryptamines, their indene isosteres and 5-hydroxytryptamine in the rat stomach fundus preparation

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12 December 2020

Behavioral effects and anticonvulsant efficacies of low-affinity, uncompetitive NMDA antagonists in mice.

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12 December 2020

The paradox of 5-methoxy-N,N-dimethyltryptamine: an indoleamine hallucinogen that induces stimulus control via 5-HT1A receptors

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12 December 2020

Analyzing mechanism(s) of hallucinogenic drug action with drug discrimination procedures.

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12 December 2020

The selective 5-HT1A antagonist radioligand [3H]WAY 100635 labels both G-protein-coupled and free 5-HT1A receptors in rat brain membranes

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12 December 2020

Further studies on the dose-dependent stimulus properties of 5-methoxy-N,N-dimethyltryptamine.

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12 December 2020

Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice

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12 December 2020

Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys

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12 December 2020

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

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12 December 2020

WAY-100635 is a potent dopamine D4 receptor agonist

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12 December 2020

Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats

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12 December 2020

Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors

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12 December 2020

Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram

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12 December 2020

Potentiation of DOM-induced stimulus control by non-competitive NMDA antagonists: a link between the glutamatergic and serotonergic hypotheses of schizophrenia.

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12 December 2020

Failure of ibogaine to produce phencyclidine-like discriminative stimulus effects in rats and monkeys

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12 December 2020

Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors

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12 December 2020

Generalization of clozapine as compared to other antipsychotic agents to a discriminative stimulus elicited by the serotonin (5-HT)2A antagonist, MDL100,907.

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12 December 2020

Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.

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12 December 2020

A three-choice discrimination procedure dissociates the discriminative stimulus effects of d-amphetamine and (+/-)-MDMA in rats.

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12 December 2020

Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis

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12 December 2020

The relative effectiveness of several hallucinogens in disrupting maze performance by rats

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12 December 2020

N-methyl-D-aspartate antagonists and drug discrimination

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12 December 2020

In vivo actions of aripiprazole on serotonergic and dopaminergic systems in rodent brain.

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12 December 2020

Complex stimulus properties of LSD: a drug discrimination study with alpha 2-adrenoceptor agonists and antagonists.

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12 December 2020

An hallucinogenic amphetamine analog (DOM) in man

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12 December 2020

Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice

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12 December 2020

A comparison of the stimulus effects of morphine and lysergic acid diethylamide (LSD).

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12 December 2020

Psilocybin-induced stimulus control in the rat.

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12 December 2020

Serum vasoconstrictor (serotonin) the presence of creatinine in the complex; a proposed structure of the vasoconstrictor principle.

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12 December 2020

Stimulus properties of phenethylamine hallucinogens and lysergic acid diethylamide: the role of 5-hydroxytryptamine

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12 December 2020

The effect of serotonin depletion on the discriminability of LSD.

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12 December 2020

Drug-induced cues in studying mechanisms of drug action

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12 December 2020

Effects of lysergic acid diethylamide upon performance of trained rats.

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12 December 2020

Tolerance and cross-tolerance among psychotomimetic drugs

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12 December 2020

Discriminative properties of phencyclidine in mice: generalization to ketamine and monohydroxy metabolites

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12 December 2020

(+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist

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12 December 2020

Antagonism between lysergic acid diethylamide and 5-hydroxytryptamine

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12 December 2020

(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists

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12 December 2020

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile

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12 December 2020

Increased discriminative stimulus potency of phencyclidine in C57B1/6 mice infected with the LP-BM5 retrovirus.

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12 December 2020

Effects of pirenperone and ketanserin on rat prolactin secretion in vivo and in vitro

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12 December 2020

Two kinds of tryptamine receptor. 1957.

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12 December 2020

The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. I: Antagonist correlation analysis

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12 December 2020

Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action

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12 December 2020

Arylalkylamine drugs of abuse: an overview of drug discrimination studies

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12 December 2020

Alteration of a learned response of the squirrel monkey by hallucinogens.

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12 December 2020

Activity of serotonin (5-HT) receptor agonists, partial agonists and antagonists at cloned human 5-HT1A receptors that are negatively coupled to adenylate cyclase in permanently transfected HeLa cells

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12 December 2020

Behavioral effects of 5-methoxy-N,N-dimethyltryptamine and dose-dependent antagonism by BC-105.

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12 December 2020

The discriminative stimulus properties of LSD: mechanisms of action

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12 December 2020

Acquired and crossed tolerance to mescaline, LSD-25, and BOL-148

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12 December 2020

Mescaline and lysergic acid diethylamide (LSD) as discriminative stimuli

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12 December 2020

Serotonin model of schizophrenia: emerging role of glutamate mechanisms

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12 December 2020

Assessment of the MDA and MDMA optical isomers in a stimulant-hallucinogen discrimination.

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12 December 2020

Lysergic acid diethylamide (LSD) as a discriminative cue: Drugs with similar stimulus properties

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12 December 2020

L-α-Methyl-β-hydrazino-β-(3,4-dihydroxyphenyl)propionic Acid: Relative Lack of Antidecarboxylase Activity in Adrenals

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12 December 2020

Role of serotonin in the discriminative stimulus properties of mescaline

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12 December 2020

The selective serotonin(2A) receptor antagonist, MDL100,907, elicits a specific interoceptive cue in rats

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12 December 2020

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice

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12 December 2020

Dopamine ligands and the stimulus effects of amphetamine: animal models versus human laboratory data

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12 December 2020

Cardiovascular effects of 2, 5-dimethoxy-4-methylamphetamine (DOM, STP).

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12 December 2020

The behavioral pharmacology of hallucinogens

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12 December 2020

5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man--a PET study with [11C]raclopride.

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12 December 2020

Mouse models for psychiatric disorders.

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12 December 2020

Study of a new schizophrenomimetic drug; sernyl.

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12 December 2020

A drug discrimination analysis of lysergic acid diethylamide (LSD): in vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD-antagonist.

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12 December 2020

Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines

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12 December 2020

Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds

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12 December 2020

Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone

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12 December 2020

A 5-HT(2C) receptor-mediated interaction between 2,5-dimethoxy-4-methylamphetamine and citalopram in the rat.

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12 December 2020

The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. III: The mechanistic basis for supersensitivity to the LSD stimulus following serotonin depletion

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12 December 2020

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12 December 2020

5-HT2A receptor-stimulated phosphoinositide hydrolysis in the stimulus effects of hallucinogens

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12 December 2020

Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis

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12 December 2020

Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance

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12 December 2020

The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site

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12 December 2020

Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice

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12 December 2020

Chronic phenethylamine hallucinogen treatment alters behavioral sensitivity to a metabotropic glutamate 2/3 receptor agonist

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12 December 2020

Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice

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12 December 2020

Do functional relationships exist between 5-HT1A and 5-HT2 receptors?

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12 December 2020

WAY-100635 has high selectivity for serotonin 5-HT(1A) versus dopamine D(4) receptors.

1 reference

12 December 2020

Assessment of the discriminative stimulus effects of the optical isomers of ecstasy (3,4-methylenedioxymethamphetamine; MDMA)

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12 December 2020

Effects of hallucinogenic and other drugs on the nest-building behaviour of mice

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12 December 2020

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12 December 2020

Serotonergic-dopaminergic mediation of MDMA's discriminative stimulus effects in a three-choice discrimination

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12 December 2020

The effect of mescaline upon the conditioned avoidance response in the rat

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12 December 2020

Comparison of tetrahydrocannabinol and synhexyl in man

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12 December 2020

Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI.

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12 December 2020

Drug discrimination by humans compared to nonhumans: current status and future directions

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12 December 2020

Hallucinogens as a discriminative stimuli: Generalization of DOM to a 5-methoxy-N, N-dimethyltryptamine stimulus

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12 December 2020

The 5-HT1A receptor agonist flesinoxan shares discriminative stimulus properties with some 5-HT2 receptor antagonists.

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12 December 2020

Hallucinogens as discriminative stimuli

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12 December 2020

Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice

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12 December 2020

The mouse: genetics meets behaviour

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12 December 2020

Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents

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12 December 2020

Tolerance to a behavioral effect of lysergic acid diethylamide and cross-tolerance to mescaline in the rat: absence of a metabolic component

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12 December 2020

Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers

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12 December 2020

Discriminative stimulus properties of lysergic acid diethylamide in the monkey.

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12 December 2020

Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex

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12 December 2020

Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats

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12 December 2020

Serotonin 5-HT2A and 5-HT2C receptors as potential targets for modulation of psychostimulant use and dependence

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12 December 2020

Inhibition of return in the human 5HT2A agonist and NMDA antagonist model of psychosis

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12 December 2020

The role of nicotinic receptor alpha 7 subunits in nicotine discrimination

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12 December 2020

Science and trans-science

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12 December 2020

Marked decrease of LSD-induced stimulus control in serotonin transporter knockout mice

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12 December 2020

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol

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12 December 2020

An experimental paradigm for studying the discriminative stimulus properties of drugs in humans.

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12 December 2020

5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediate opposing responses on membrane excitability in rat association cortex

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12 December 2020

Behavioral effects of AMI-193, a 5-HT(2A)- and dopamine D(2)-receptor antagonist, in the squirrel monkey

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12 December 2020

10.1007/S00213-008-1356-8

Identifiers

DOI

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19 August 2017

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PubMed ID

18979087