Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model (Q37325233)

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English	Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

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based on heuristic

inferred from title

cervix uterine cancer

1 reference

based on heuristic

inferred from title

author name string

Dingqing Feng

1

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Europe PubMed Central

PMC publication ID

19 August 2017

Jiao Wu

2

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Europe PubMed Central

PMC publication ID

19 August 2017

Yuan Tian

3

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Europe PubMed Central

PMC publication ID

19 August 2017

Hu Zhou

4

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Europe PubMed Central

PMC publication ID

19 August 2017

Ying Zhou

5

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Europe PubMed Central

PMC publication ID

19 August 2017

Weiping Hu

6

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Europe PubMed Central

PMC publication ID

19 August 2017

Weidong Zhao

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Haiming Wei

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Bin Ling

9

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Europe PubMed Central

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19 August 2017

Chunhong Ma

10

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Europe PubMed Central

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19 August 2017

language of work or name

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publication date

19 November 2013

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Europe PubMed Central

PMC publication ID

19 August 2017

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Europe PubMed Central

PMC publication ID

19 August 2017

8

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Europe PubMed Central

PMC publication ID

19 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

e80657

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

19 November 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression

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Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells

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6 September 2017

Effects of treatment with histone deacetylase inhibitors in solid tumors: a review based on 30 clinical trials

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6 September 2017

Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers

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6 September 2017

Role of histone deacetylases in gene regulation at nuclear lamina.

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6 September 2017

Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3.

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6 September 2017

Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance

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6 September 2017

The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models

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6 September 2017

Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL.

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6 September 2017

Combination of valproic acid and ATRA restores RARβ2 expression and induces differentiation in cervical cancer through the PI3K/Akt pathway

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6 September 2017

Anticancer drugs aimed at E6 and E7 activity in HPV-positive cervical cancer.

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6 September 2017

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

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6 September 2017

Epigenetic targets in human neoplasms

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6 September 2017

Cellular senescence and tumor suppressor gene p16

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6 September 2017

E-cadherin/β-catenin complex and the epithelial barrier

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6 September 2017

Promoter methylation of E-cadherin, p16, and RAR-β(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism

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6 September 2017

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

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6 September 2017

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

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6 September 2017

Interactive Roles of Ets-1, Sp1, and Acetylated Histones in the Retinoic Acid-dependent Activation of Guanylyl Cyclase/Atrial Natriuretic Peptide Receptor-A Gene Transcription

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6 September 2017

Studies on Multifunctional Effect of All-Trans Retinoic Acid (ATRA) on Matrix Metalloproteinase-2 (MMP-2) and Its Regulatory Molecules in Human Breast Cancer Cells (MCF-7).

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6 September 2017

Genomic antagonism between retinoic acid and estrogen signaling in breast cancer.

1 reference

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6 September 2017

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation

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6 September 2017

Histone deacetylase inhibitors: molecular mechanisms of action

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834007

6 September 2017

Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors

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6 September 2017

Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid

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6 September 2017

Retinoic acid and retinoid receptors: potential chemopreventive and therapeutic role in cervical cancer

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6 September 2017

Molecular requirements for epithelial-mesenchymal transition during tumor progression

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6 September 2017

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

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6 September 2017

Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834007

6 September 2017

Histone Deacetylation of RB-Responsive Promoters: Requisite for Specific Gene Repression but Dispensable for Cell Cycle Inhibition

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6 September 2017

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

1 reference

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6 September 2017

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

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6 September 2017

Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues

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Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis

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14 September 2017

Global reactivation of epigenetically silenced genes in prostate cancer

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14 September 2017

Acyclic retinoid synergises with valproic acid to inhibit growth in human hepatocellular carcinoma cells

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14 September 2017

Epigenetic patterns of the retinoic acid receptor beta2 promoter in retinoic acid-resistant thyroid cancer cells

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14 September 2017

Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model

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14 September 2017

Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

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14 September 2017

Differentiation and antiproliferation effects of retinoic acid receptor beta in hepatoma cells

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28 September 2017

Altered expression of cell-cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors

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26 June 2018

Experimental model for combination chemotherapy with metronidazole using human uterine cervical carcinomas transplanted into nude mice

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26 June 2018

A phase I study of quisinostat (JNJ-26481585), an oral hydroxamate histone deacetylase inhibitor with evidence of target modulation and antitumor activity, in patients with advanced solid tumors.

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2 September 2018

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2 September 2018

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2 September 2018

Reduced aquaporin3 expression and survival of keratinocytes in the depigmented epidermis of vitiligo.

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2 September 2018

Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death.

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2 September 2018

Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy

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2 September 2018

Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways

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2 September 2018

Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines

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12 December 2020

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Significance of E-cadherin, β-catenin, and vimentin expression as postoperative prognosis indicators in cervical squamous cell carcinoma

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https://pubmed.ncbi.nlm.nih.gov/24260446

12 December 2020

based on heuristic

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Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24260446

12 December 2020

based on heuristic

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Upregulation of vimentin and aberrant expression of E-cadherin/beta-catenin complex in oral squamous cell carcinomas: correlation with the clinicopathological features and patient outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24260446

12 December 2020

based on heuristic

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Identifiers

10.1371/JOURNAL.PONE.0080657

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Europe PubMed Central

PMC publication ID

19 August 2017

2013PLoSO...880657F

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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