Efficient siRNA delivery with non-viral polymeric vehicles (Q37328068)

19 August 2017

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title

Efficient siRNA delivery with non-viral polymeric vehicles (English)

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19 August 2017

Won Jong Kim

1

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PubMed ID

19015957

19 August 2017

Sung Wan Kim

series ordinal

2

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19 August 2017

18 November 2008

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19 August 2017

Pharmaceutical Research

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19 August 2017

26

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19 August 2017

3

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19 August 2017

657-666

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Biodistribution and metabolism of a mixed backbone oligonucleotide (GEM 231) following single and multiple dose administration in mice.

19 August 2017

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-008-9774-1

RNA interference in mammalian cells by chemically-modified RNA.

21 January 2018

1 reference

12 December 2020

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

12 December 2020

Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro.

1 reference

12 December 2020

Interfering with disease: a progress report on siRNA-based therapeutics

1 reference

12 December 2020

Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells

1 reference

12 December 2020

Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy

1 reference

12 December 2020

The cellular delivery of antisense oligonucleotides and ribozymes

1 reference

12 December 2020

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

1 reference

12 December 2020

Size reduction of galactosylated PEI/DNA complexes improves lectin-mediated gene transfer into hepatocytes

1 reference

12 December 2020

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

12 December 2020

Escort aptamers: a delivery service for diagnosis and therapy

1 reference

12 December 2020

Strategies for silencing human disease using RNA interference

1 reference

12 December 2020

Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies.

1 reference

12 December 2020

High affinity ligands from in vitro selection: complex targets.

1 reference

12 December 2020

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

1 reference

12 December 2020

The third helix of the Antennapedia homeodomain translocates through biological membranes.

1 reference

12 December 2020

Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine

1 reference

12 December 2020

A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

1 reference

12 December 2020

Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium

1 reference

12 December 2020

Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging

1 reference

12 December 2020

Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine

1 reference

12 December 2020

Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-tapgeted gene carrier

1 reference

12 December 2020

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma

1 reference

12 December 2020

Water-soluble lipopolymer for gene delivery

1 reference

12 December 2020

Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen

1 reference

12 December 2020

Comparative evaluation of target-specific GFP gene silencing efficiencies for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate

1 reference

12 December 2020

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

1 reference

12 December 2020

RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA.

1 reference

12 December 2020

Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer

1 reference

12 December 2020

Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol

1 reference

12 December 2020

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

1 reference

12 December 2020

Characterisation of cell-penetrating peptide-mediated peptide delivery

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12 December 2020

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

1 reference

12 December 2020

Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.

1 reference

12 December 2020

Hypoxia-inducible VEGF gene delivery to ischemic myocardium using water-soluble lipopolymer

1 reference

12 December 2020

Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery

1 reference

12 December 2020

Tolerance for mutations and chemical modifications in a siRNA.

1 reference

12 December 2020

Aptamer mediated siRNA delivery

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12 December 2020

A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids

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12 December 2020

Biodegradable poly(ethylenimine) for plasmid DNA delivery

1 reference

12 December 2020

Rational siRNA design for RNA interference

1 reference

12 December 2020

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

12 December 2020

Reducible poly(amido ethylenimine) directed to enhance RNA interference

1 reference

12 December 2020

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

12 December 2020

The design and exogenous delivery of siRNA for post-transcriptional gene silencing.

1 reference

12 December 2020

A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment

1 reference

12 December 2020

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

1 reference

12 December 2020

RNAi-mediated gene silencing in non-human primates.

1 reference

12 December 2020

RNA interference: from gene silencing to gene-specific therapeutics

1 reference

12 December 2020

Tumor regression by repeated intratumoral delivery of water soluble lipopolymers/p2CMVmIL-12 complexes

1 reference

12 December 2020

Cell-specific delivery of genes with glycosylated carriers

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12 December 2020

The delivery of antisense therapeutics

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12 December 2020

Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells.

1 reference

12 December 2020

Possible existence of common internalization mechanisms among arginine-rich peptides

1 reference

12 December 2020

Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

1 reference

12 December 2020

Transferrin receptor 1.

1 reference

12 December 2020

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

1 reference

12 December 2020

siRNA function in RNAi: a chemical modification analysis

1 reference

12 December 2020

Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides

1 reference

12 December 2020

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

1 reference

12 December 2020

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

1 reference

12 December 2020

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

1 reference

12 December 2020

Transfection of folate-polylysine DNA complexes: evidence for lysosomal delivery

1 reference

12 December 2020

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

1 reference

12 December 2020

Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice

1 reference

12 December 2020

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

1 reference

12 December 2020

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

12 December 2020

Chemical modification: the key to clinical application of RNA interference?

1 reference

12 December 2020

Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles

1 reference

12 December 2020

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

1 reference

12 December 2020

Specific beta1-adrenergic receptor silencing with small interfering RNA lowers high blood pressure and improves cardiac function in myocardial ischemia

1 reference

12 December 2020

Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo

1 reference

12 December 2020

Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo.

1 reference

12 December 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

1 reference

12 December 2020

RNAi therapeutics: a potential new class of pharmaceutical drugs

1 reference

12 December 2020

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

1 reference

12 December 2020

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

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12 December 2020

Progress towards in vivo use of siRNAs

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12 December 2020

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

1 reference

12 December 2020

Targeted delivery systems of small interfering RNA by systemic administration

1 reference

12 December 2020

Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung

1 reference

12 December 2020

Target-specific gene silencing by siRNA plasmid DNA complexed with folate-modified poly(ethylenimine).

1 reference

12 December 2020

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

1 reference

12 December 2020

Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma

1 reference

12 December 2020

A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes

1 reference

12 December 2020

Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis

1 reference

12 December 2020

Polyethylene glycol-conjugated copolymers for plasmid DNA delivery

1 reference

12 December 2020

Characterization of commercially available and synthesized polyethylenimines for gene delivery

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12 December 2020

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

1 reference

12 December 2020

Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity

1 reference

12 December 2020

Endocytosis of folate-protein conjugates: ultrastructural localization in KB cells

1 reference

12 December 2020

Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

1 reference

12 December 2020

10.1007/S11095-008-9774-1

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19015957