Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. (Q37329670)

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6 February 2020

title

Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity (English)

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1

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10

Cedric S Raine

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6 February 2020

author name string

Sawsan Youssef

2

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Eun Mi Hur

3

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Peggy P Ho

4

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May H Han

5

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Tobias V Lanz

6

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6 February 2020

Lori K Phillips

7

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Matthew J Goldstein

8

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Roopa Bhat

9

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Raymond A Sobel

11

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Lawrence Steinman

12

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language of work or name

English

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publication date

19 August 2009

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Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

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volume

106

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issue

35

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6 February 2020

page(s)

14948-14953

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Cytokine signaling modules in inflammatory responses

6 February 2020

cites work

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6 September 2017

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Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction

6 September 2017

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6 September 2017

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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

6 September 2017

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Human regulatory T cells and their role in autoimmune disease

6 September 2017

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The immune response in atherosclerosis: a double-edged sword

6 September 2017

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Mechanisms of disease: local renin-angiotensin-aldosterone systems and the pathogenesis and treatment of cardiovascular disease

6 September 2017

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Design of effective immunotherapy for human autoimmunity

6 September 2017

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Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

6 September 2017

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Autoimmune and inflammatory mechanisms in atherosclerosis

6 September 2017

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Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

6 September 2017

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Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation

6 September 2017

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Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis

6 September 2017

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

6 September 2017

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Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

6 September 2017

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History of the design of captopril and related inhibitors of angiotensin converting enzyme

6 September 2017

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Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing

6 September 2017

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Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling

14 September 2017

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Angiotensin-converting enzyme I/D gene polymorphism and risk of multiple sclerosis.

28 September 2017

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Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice

2 September 2018

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2 September 2018

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The non-thiol angiotensin-converting enzyme inhibitor quinapril suppresses inflammatory arthritis

2 September 2018

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Beta blocker and angiotensin-converting enzyme inhibitor therapy is associated with decreased Th1/Th2 cytokine ratios and inflammatory cytokine production in patients with chronic heart failure

2 September 2018

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2 September 2018

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SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

3 December 2018

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12 December 2020

Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-/- mice

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12 December 2020

Effects of the angiotensin converting enzyme inhibitor captopril on experimental autoimmune encephalomyelitis

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12 December 2020

Serum angiotensin-converting enzyme in multiple sclerosis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0903958106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706421%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

0 references

1 reference

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6 February 2020

PubMed publication ID

19706421

1 reference