Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. (Q37333234)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561184%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins (English)

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1 February 2020

2

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1 February 2020

Colin Hill

series ordinal

3

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1 February 2020

Reynolds Paul Ross

series ordinal

4

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1 February 2020

author name string

Máire Begley

series ordinal

1

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1 February 2020

language of work or name

English

0 references

publication date

26 June 2009

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Applied and Environmental Microbiology

1 February 2020

published in

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1 February 2020

volume

75

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1 February 2020

issue

17

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1 February 2020

page(s)

5451-5460

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Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniaeSpain23F ST81

1 February 2020

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5

6 September 2017

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Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells

6 September 2017

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Bacterial lantibiotics: strategies to improve therapeutic potential.

6 September 2017

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Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species

6 September 2017

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The Enterococcus faecalis cytolysin: a novel toxin active against eukaryotic and prokaryotic cells

6 September 2017

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Purification and Characterization of Streptin, a Type A1 Lantibiotic Produced by Streptococcus pyogenes

6 September 2017

1 reference

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Mode of action of modified and unmodified bacteriocins from Gram-positive bacteria

6 September 2017

1 reference

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Ribosomally synthesized antibacterial peptides in Gram positive bacteria

6 September 2017

1 reference

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Multiple activities in lantibiotics--models for the design of novel antibiotics?

6 September 2017

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Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics

6 September 2017

1 reference

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Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Purification of mutacin III from group III Streptococcus mutans UA787 and genetic analyses of mutacin III biosynthesis genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Two-component anti-Staphylococcus aureus lantibiotic activity produced by Staphylococcus aureus C55

6 September 2017

1 reference

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

6 September 2017

1 reference

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Comparison of lantibiotic gene clusters and encoded proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

An application in cheddar cheese manufacture for a strain of Lactococcus lactis producing a novel broad-spectrum bacteriocin, lacticin 3147.

6 September 2017

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Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence

6 September 2017

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Molecular characterization of the Enterococcus faecalis cytolysin activator

6 September 2017

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Biosynthesis of the lantibiotic mersacidin: organization of a type B lantibiotic gene cluster

6 September 2017

1 reference

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Characterization of the gene cluster involved in the biosynthesis of macedocin, the lantibiotic produced by Streptococcus macedonicus

14 September 2017

1 reference

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26 June 2018

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Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147.

26 June 2018

1 reference

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Analysis of genes involved in the biosynthesis of lantibiotic epidermin

26 June 2018

1 reference

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Isolation and partial characterization of the Streptococcus mutans type AII lantibiotic mutacin K8.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

In vivo activity of mutacin B-Ny266.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737927

Covalent structure of mutacin 1140 and a novel method for the rapid identification of lantibiotics

2 September 2018

1 reference

12 December 2020

Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic

1 reference

12 December 2020

Pep5, a new lantibiotic: structural gene isolation and prepeptide sequence

1 reference

12 December 2020

A lantibiotic gene family widely distributed in Streptococcus salivarius and Streptococcus pyogenes

1 reference

12 December 2020

Purification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans

1 reference

12 December 2020

Antibacterial efficacy of nisin against multidrug-resistant Gram- positive pathogens

1 reference

12 December 2020

The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II

1 reference

12 December 2020

Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125

1 reference

12 December 2020

Identifiers

DOI

10.1128/AEM.00730-09

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561184%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19561184%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

19561184

1 reference