Computational evaluation of cellular metabolic costs successfully predicts genes whose expression is deleterious (Q37340891)

19 August 2017

Computational evaluation of cellular metabolic costs successfully predicts genes whose expression is deleterious (English)

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19 August 2017

1

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5 June 2020

Uri Gophna

6

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5 June 2020

author name string

Raphy Zarecki

2

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5 June 2020

Leah Reshef

3

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5 June 2020

Camelia Gochev

4

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5 June 2020

Rotem Sorek

5

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5 June 2020

Eytan Ruppin

7

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5 June 2020

language of work or name

English

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publication date

6 November 2013

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Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

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5 June 2020

volume

110

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5 June 2020

issue

47

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5 June 2020

page(s)

19166-19171

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Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools

5 June 2020

cites work

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models

6 September 2017

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Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation

6 September 2017

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The biomass objective function

6 September 2017

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OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

6 September 2017

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What is flux balance analysis?

6 September 2017

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The landscape of somatic copy-number alteration across human cancers

6 September 2017

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Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

6 September 2017

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The genetic landscape of a cell

6 September 2017

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AraGEM, a genome-scale reconstruction of the primary metabolic network in Arabidopsis

6 September 2017

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6 September 2017

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6 September 2017

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iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations

6 September 2017

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Gene expression profiling and the use of genome-scale in silico models of Escherichia coli for analysis: providing context for content

6 September 2017

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6 September 2017

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Systems metabolic engineering of Escherichia coli for L-threonine production

6 September 2017

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A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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A gene expression map of Arabidopsis thaliana development

6 September 2017

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A gene atlas of the mouse and human protein-encoding transcriptomes

6 September 2017

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The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

6 September 2017

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6 September 2017

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Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

6 September 2017

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Gene expression profiling predicts clinical outcome of breast cancer

6 September 2017

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Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates.

6 September 2017

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Metabolic flux elucidation for large-scale models using 13C labeled isotopes

14 September 2017

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

26 June 2018

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Overexpression of Agrt leads to obesity in transgenic mice.

26 June 2018

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Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain

26 June 2018

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An integrated computational and experimental study for overproducing fatty acids in Escherichia coli.

26 June 2018

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Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids.

2 September 2018

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Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering.

2 September 2018

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Geobacter sulfurreducens strain engineered for increased rates of respiration

2 September 2018

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Genome-wide experimental determination of barriers to horizontal gene transfer.

2 September 2018

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Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

2 September 2018

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An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems

2 September 2018

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Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

2 September 2018

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Characterizing the metabolic phenotype: a phenotype phase plane analysis

2 September 2018

1 reference

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Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1312361110

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1312361110

21 January 2018

Identifiers

DOI

10.1073/PNAS.1312361110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198337%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198337%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

24198337

1 reference