X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice. (Q37343310)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice (English)

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3 February 2020

0 references

0 references

4

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3 February 2020

author name string

Inderjeet Saluja

series ordinal

1

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3 February 2020

Henry Paulson

series ordinal

2

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3 February 2020

Ashwin Gupta

series ordinal

3

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publication date

23 July 2009

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3 February 2020

published in

Neurobiology of Disease

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3 February 2020

volume

36

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issue

1

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3 February 2020

page(s)

162-168

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describes a project that uses

3 February 2020

ImageQuant

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11 June 2022

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cites work

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Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein

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Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease

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Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting

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The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

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Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha.

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RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

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The Neuronal Adaptor Protein X11β Reduces Amyloid β-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19631749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/19631749

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NBD.2009.07.006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

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3 February 2020

PubMed publication ID

19631749

1 reference