Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use. (Q37344283)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24167321%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use (English)

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28 February 2020

1 reference

2

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28 February 2020

Christine E Brown

10

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28 February 2020

Philip M Potter

12

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28 February 2020

Timothy Synold

14

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15

Karen S Aboody

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28 February 2020

3

Simon F Lacey

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28 February 2020

author name string

Marianne Z Metz

1

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28 February 2020

Yelena Abramyants

4

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28 February 2020

Tien Vo

5

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28 February 2020

Megan Gilchrist

6

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28 February 2020

Revathiswari Tirughana

7

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28 February 2020

Lucy Y Ghoda

8

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28 February 2020

Michael E Barish

9

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28 February 2020

Joseph Najbauer

11

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Jana Portnow

13

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28 February 2020

publication date

28 October 2013

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Stem Cells Translational Medicine

28 February 2020

published in

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volume

2

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28 February 2020

issue

12

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28 February 2020

page(s)

983-992

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Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies

28 February 2020

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6 September 2017

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Translational research in brain metastasis is identifying molecular pathways that may lead to the development of new therapeutic strategies

6 September 2017

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6 September 2017

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Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model

6 September 2017

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6 September 2017

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Malignant gliomas in adults

6 September 2017

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Stem and progenitor cell-mediated tumor selective gene therapy

6 September 2017

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Technology insight: cytotoxic drug immunoconjugates for cancer therapy

6 September 2017

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Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma

6 September 2017

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6 September 2017

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Topoisomerase I inhibitors: camptothecins and beyond

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition

6 September 2017

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Structural insights into CPT-11 activation by mammalian carboxylesterases

6 September 2017

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Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

6 September 2017

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6 September 2017

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Intracellular dynamics of topoisomerase I inhibitor, CPT-11, by slit-scanning confocal Raman microscopy

6 September 2017

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Neural stem cell tropism to glioma: critical role of tumor hypoxia.

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11).

14 September 2017

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Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11.

28 September 2017

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Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Application to a rabbit liver carboxylesterase

26 June 2018

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Genetically engineered human neural stem cells with rabbit carboxyl esterase can target brain metastasis from breast cancer

26 June 2018

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An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.

2 September 2018

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Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice

2 September 2018

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Enzyme-prodrug systems: carboxylesterase/CPT-11.

2 September 2018

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Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase

2 September 2018

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Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

2 September 2018

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2 September 2018

Identifiers

DOI

10.5966/SCTM.2012-0177

1 reference

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release_inbgf2uoi5c6bdygsqt7db46pe

28 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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28 February 2020

PubMed publication ID

24167321

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