Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product (Q28209604)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11477403%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product (English)

1 reference

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Signaling lymphocytic activation molecule family member 1

9 November 2019

main subject

1 reference

GOA release 2020-03-11

author

Sylvain Latour

1

1 reference

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9 November 2019

Richard Humphries

4

1 reference

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9 November 2019

author name string

G Gish

2

1 reference

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9 November 2019

C D Helgason

3

1 reference

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9 November 2019

T Pawson

5

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9 November 2019

A Veillette

6

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9 November 2019

language of work or name

English

0 references

publication date

1 August 2001

1 reference

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9 November 2019

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9 November 2019

volume

2

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9 November 2019

issue

8

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9 November 2019

page(s)

681-690

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X-linked lymphoproliferative disease: a progressive immunodeficiency

9 November 2019

cites work

1 reference

X-linked lymphoproliferative disease is caused by deficiency of a novel SH2 domain-containing signal transduction adaptor protein

21 January 2018

1 reference

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

21 January 2018

1 reference

Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome

21 January 2018

1 reference

Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

21 January 2018

1 reference

A novel receptor involved in T-cell activation

21 January 2018

1 reference

Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4.

21 January 2018

1 reference

Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity

21 January 2018

1 reference

Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome

21 January 2018

1 reference

X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells

21 January 2018

1 reference

2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism

21 January 2018

1 reference

Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A

21 January 2018

1 reference

Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

21 January 2018

1 reference

Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

21 January 2018

1 reference

The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells

21 January 2018

1 reference

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

21 January 2018

1 reference

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

1 reference

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

21 January 2018

1 reference

Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins

21 January 2018

1 reference

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

21 January 2018

1 reference

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn

21 January 2018

1 reference

The Src and Csk families of tyrosine protein kinases in hemopoietic cells.

21 January 2018

1 reference

Signal transduction by lymphocyte antigen receptors

21 January 2018

1 reference

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

21 January 2018

1 reference

Tec kinases: a family with multiple roles in immunity

21 January 2018

1 reference

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase

21 January 2018

1 reference

Identification of a monoclonal antibody specific for a murine T3 polypeptide

21 January 2018

1 reference

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

21 January 2018

1 reference

The SH2 domain is required for stable phosphorylation of p56lck at tyrosine 505, the negative regulatory site

21 January 2018

1 reference

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

21 January 2018

1 reference

SAP controls T cell responses to virus and terminal differentiation of TH2 cells.

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac

1 reference