Phosphodiesterase inhibition in heart failure (Q37355108)

19 August 2017

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title

Phosphodiesterase inhibition in heart failure (English)

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19 August 2017

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Matthew Movsesian

1

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19 August 2017

Josef Stehlik

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2

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19 August 2017

Fabrice Vandeput

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3

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19 August 2017

Michael R Bristow

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4

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19 August 2017

19 December 2008

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19 August 2017

Heart Failure Reviews

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19 August 2017

14

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19 August 2017

255-263

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19 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s10741-008-9130-x

19 August 2017

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cites work

Characteristics of the beta-adrenergic receptor complex in the epicardial border zone of the 5-day infarcted canine heart

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

The molecular basis for distinct beta-adrenergic receptor subtype actions in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

Compartmentation of cAMP in adult canine ventricular myocytes. Relation to single-cell free Ca2+ transients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

Ontogenetic changes in adenylate cyclase, cyclic AMP phosphodiesterase and calmodulin in chick ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-008-9130-X

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide

21 January 2018

1 reference

12 December 2020

Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB.

1 reference

12 December 2020

Low-dose oral enoximone enhances the ability to wean patients with ultra-advanced heart failure from intravenous inotropic support: results of the oral enoximone in intravenous inotrope-dependent subjects trial

1 reference

12 December 2020

Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study

1 reference

12 December 2020

Effects of sildenafil (viagra) on human myocardial contractility, in vitro arrhythmias, and tension of internal mammaria arteries and saphenous veins

1 reference

12 December 2020

Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.

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12 December 2020

A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.

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12 December 2020

ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association

1 reference

12 December 2020

Oral sildenafil reduces pulmonary hypertension after cardiac surgery

1 reference

12 December 2020

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

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12 December 2020

Sildenafil citrate therapy for pulmonary arterial hypertension

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12 December 2020

Pharmacologic and hemodynamic effects of combined beta-agonist stimulation and phosphodiesterase inhibition in the failing human heart

1 reference

12 December 2020

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

1 reference

12 December 2020

Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men.

1 reference

12 December 2020

Increased effects of C-type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP-dependent protein kinase I.

1 reference

12 December 2020

Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: results of a multicenter study in the United States

1 reference

12 December 2020

Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice

1 reference

12 December 2020

Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure

1 reference

12 December 2020

Evaluation of a new bipyridine inotropic agent--milrinone--in patients with severe congestive heart failure

1 reference

12 December 2020

Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.

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12 December 2020

Potentiation of slow component of delayed rectifier K(+) current by cGMP via two distinct mechanisms: inhibition of phosphodiesterase 3 and activation of protein kinase G.

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12 December 2020

Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial

1 reference

12 December 2020

Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations

1 reference

12 December 2020

The year in heart failure

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12 December 2020

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

1 reference

12 December 2020

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

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12 December 2020

Phosphodiesterase inhibition improves agonist-induced relaxation of hypertensive pulmonary arteries

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12 December 2020

Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes

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12 December 2020

cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium

1 reference

12 December 2020

Effect of sildenafil on arterial stiffness and wave reflection

1 reference

12 December 2020

Cyclic nucleotide hydrolysis in bovine aortic endothelial cells in culture: differential regulation in cobblestone and spindle phenotypes

1 reference

12 December 2020

Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes

1 reference

12 December 2020

Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside

1 reference

12 December 2020

Effects of vesnarinone on morbidity and mortality in patients with heart failure. Vesnarinone Study Group

1 reference

12 December 2020

Positive chronotropic and inotropic effects of C-type natriuretic peptide in dogs

1 reference

12 December 2020

Reduced Ca(2+)-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phosphorylation

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12 December 2020

Evidence for selective regulation of the phosphorylation of myocyte proteins by isoproterenol and prostaglandin E1

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12 December 2020

Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes

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12 December 2020

Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium

1 reference

12 December 2020

Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide

1 reference

12 December 2020

Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

1 reference

12 December 2020

Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts

1 reference

12 December 2020

A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure

1 reference

12 December 2020

Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1

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12 December 2020

Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension.

1 reference

12 December 2020

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

1 reference

12 December 2020

Long-Term Treatment With Oral Sildenafil Is Safe and Improves Functional Capacity and Hemodynamics in Patients With Pulmonary Arterial Hypertension

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12 December 2020

Beta 1-adrenoceptor stimulation and beta 2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells

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12 December 2020

Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.

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12 December 2020

C-type natriuretic peptide increases myocardial contractility and sinus rate mediated by guanylyl cyclase-linked natriuretic peptide receptors in isolated, blood-perfused dog heart preparations.

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12 December 2020

Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin T

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12 December 2020

Rationale and design of the enoximone clinical trials program

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12 December 2020

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

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12 December 2020

Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility

1 reference

12 December 2020

A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators

1 reference

12 December 2020

Milrinone: basic and clinical pharmacology and acute and chronic management

1 reference

12 December 2020

Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current

1 reference

12 December 2020

Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes

1 reference

12 December 2020

Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study

1 reference

12 December 2020

Sildenafil effects on exercise, neurohormonal activation, and erectile dysfunction in congestive heart failure: a double-blind, placebo-controlled, randomized study followed by a prospective treatment for erectile dysfunction.

1 reference

12 December 2020

Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits

1 reference

12 December 2020

Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure. Lack of benefit compared with placebo. Enoximone Multicenter Trial Group

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12 December 2020

Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A.

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12 December 2020

Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts.

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12 December 2020

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

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12 December 2020

Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans

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12 December 2020

cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism

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12 December 2020

Reduced gene expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure

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12 December 2020

Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes.

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12 December 2020

cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes

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12 December 2020

Long-term therapy with a new cardiotonic agent, WIN 47203: drug-dependent improvement in cardiac performance and progression of the underlying disease

1 reference

12 December 2020

Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure

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12 December 2020

Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

1 reference

12 December 2020

The effects of phosphodiesterase-5 inhibition with sildenafil on pulmonary hemodynamics and diffusion capacity, exercise ventilatory efficiency, and oxygen uptake kinetics in chronic heart failure

1 reference

12 December 2020

Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes

1 reference

12 December 2020

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

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12 December 2020

In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE).

1 reference

12 December 2020

Increased effects of C-type natriuretic peptide on cardiac ventricular contractility and relaxation in guanylyl cyclase A-deficient mice

1 reference

12 December 2020

Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study

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12 December 2020

Pharmacological management of erectile dysfunction

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12 December 2020

Basal and isoprenaline-stimulated cAMP content in failing versus nonfailing human cardiac preparations

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12 December 2020

Long-term use of sildenafil in the therapeutic management of heart failure

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12 December 2020

Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes

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12 December 2020

A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure

1 reference

12 December 2020

Hemodynamic assessment of amrinone. A new inotropic agent

1 reference

12 December 2020

Systemic and coronary effects of intravenous milrinone and dobutamine in congestive heart failure

1 reference

12 December 2020

cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

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12 December 2020

Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta

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12 December 2020

A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy

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12 December 2020

Low-dose enoximone improves exercise capacity in chronic heart failure. Enoximone Study Group

1 reference

12 December 2020

Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells

1 reference

12 December 2020

Efficacy and safety of sildenafil in the evaluation of pulmonary hypertension in severe heart failure

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12 December 2020

Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

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12 December 2020

Beta 2-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation

1 reference

12 December 2020

10.1007/S10741-008-9130-X

Identifiers

DOI

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19 August 2017

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