Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. (Q37357807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15070740%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells (English)

1 reference

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26 December 2019

2

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26 December 2019

Eva Hernando

4

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26 December 2019

author name string

Loren Michel

1

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26 December 2019

Gopeshwar Narayan

3

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26 December 2019

Vundavalli V V S Murty

5

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26 December 2019

Robert Benezra

6

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26 December 2019

language of work or name

English

0 references

publication date

15 March 2004

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

26 December 2019

published in

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26 December 2019

volume

101

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26 December 2019

issue

13

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26 December 2019

page(s)

4459-4464

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Mad2 phosphorylation regulates its association with Mad1 and the APC/C.

26 December 2019

cites work

1 reference

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Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2

6 September 2017

1 reference

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APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit

6 September 2017

1 reference

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The anaphase-promoting complex: proteolysis in mitosis and beyond

6 September 2017

1 reference

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

6 September 2017

1 reference

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Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase

6 September 2017

1 reference

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Tracing the pathway of spindle assembly checkpoint signaling

6 September 2017

1 reference

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The mitotic spindle: a self-made machine

6 September 2017

1 reference

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Degradation of the kinesin Kip1p at anaphase onset is mediated by the anaphase-promoting complex and Cdc20p

6 September 2017

1 reference

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Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression

6 September 2017

1 reference

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Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Mitotic checkpoints: from yeast to cancer

6 September 2017

1 reference

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RNA interference is mediated by 21- and 22-nucleotide RNAs

6 September 2017

1 reference

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The spindle cycle in budding yeast

6 September 2017

1 reference

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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Identification of a human mitotic checkpoint gene: hsMAD2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Feedback control of mitosis in budding yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Electron-microscopic study of the spindle and chromosome movement in the yeast Saccharomyces cerevisiae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Role of p53 in UVB-induced apoptosis in human HaCaT keratinocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384769

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15070740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Exit from Mitosis in Budding Yeast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15070740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0306069101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15070740%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

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release_fowshpnhxndaxgjk5doy2brh2q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fowshpnhxndaxgjk5doy2brh2q

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15070740%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference