Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource (Q37358904)

19 August 2017

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource (English)

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19 August 2017

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2

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19 August 2017

Matthew Hardy

10

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Calliope A. Dendrou

Calliope A Dendrou

1

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Oliver Burren

Oliver Burren

11

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John R Bradley

John R Bradley

16

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Neil M Walker

Neil M Walker

13

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Nicholas J. Wareham

17

Nicholas J Wareham

1 reference

19 August 2017

15

Willem H Ouwehand

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19 August 2017

18

John A Todd

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19 August 2017

19

Linda S Wicker

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19 August 2017

7

Sarah Nutland

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19 August 2017

5

Kate Downes

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19 August 2017

4

Jennie H M Yang

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19 August 2017

8

Gillian Coleman

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19 August 2017

12

Barry Healy

1 reference

19 August 2017

Erik Fung

3

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19 August 2017

Jason D Cooper

6

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19 August 2017

Matthew Himsworth

9

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19 August 2017

Kerstin Koch

14

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19 August 2017

language of work or name

English

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publication date

23 August 2009

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19 August 2017

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19 August 2017

41

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19 August 2017

9

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19 August 2017

1011-1015

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Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

A prescription for human immunology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Shared and distinct genetic variants in type 1 diabetes and celiac disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

RNA-Seq: a revolutionary tool for transcriptomics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Mapping and quantifying mammalian transcriptomes by RNA-Seq

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Risk alleles for multiple sclerosis identified by a genomewide study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

FOXP3 controls regulatory T cell function through cooperation with NFAT

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

A function for interleukin 2 in Foxp3-expressing regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

The quantal theory of how the immune system discriminates between "self and non-self"

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Fas and the art of lymphocyte maintenance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Purification and chemical characterization of the receptor for interleukin 2 from activated human T lymphocytes and from a human T-cell lymphoma cell line

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Progress and challenges in genome-wide association studies in humans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

The monocyte interleukin-2 receptor light chain: production of cell-associated and soluble interleukin-2 receptor by monocytes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2749506

The habitual, diverse and surmountable obstacles to human immunology research

2 September 2018

1 reference

12 December 2020

Enhancing the sensitivity of assays to detect T cell reactivity: the effect of cell separation and cryopreservation media

1 reference

12 December 2020

Decreased synthesis of interleukin-2 (IL-2) in insulin-dependent diabetes mellitus

1 reference

12 December 2020

Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice

1 reference

12 December 2020

Acquired defect in interleukin-2 production in patients with type I diabetes mellitus

1 reference

12 December 2020

Identifiers

DOI

10.1038/NG.434

1 reference

Dimensions Publication ID

19 August 2017

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1 reference

19 August 2017

PubMed publication ID

19701192

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