LX211 (voclosporin) suppresses experimental uveitis and inhibits human T cells (Q37361237)

19 August 2017

LX211 (voclosporin) suppresses experimental uveitis and inhibits human T cells (English)

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19 August 2017

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6

Chi-Chao Chan

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19 August 2017

Robert B. Nussenblatt

9

object named as

Robert B Nussenblatt

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19 August 2017

Matthew A Cunningham

1

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19 August 2017

Bobbie Ann Austin

2

1 reference

19 August 2017

Zhuqing Li

3

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19 August 2017

Baoying Liu

4

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19 August 2017

Steven Yeh

5

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19 August 2017

Eddy Anglade

7

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19 August 2017

Poonam Velagaleti

8

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19 August 2017

language of work or name

English

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publication date

15 August 2008

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Investigative Ophthalmology Visual Science

19 August 2017

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19 August 2017

50

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19 August 2017

1

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19 August 2017

249-255

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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Next-generation calcineurin inhibitors for ophthalmic indications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Topical cyclosporine for treatment of ocular surface disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Intravitreal injection of Tacrolimus (FK506) suppresses ongoing experimental autoimmune uveoretinitis in Rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Oxidative and nitrosative stress in kidney disease: a case for cyclosporine A.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Biochemical mechanisms of cyclosporine neurotoxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Systemic CD4(+) T cell phenotype and activation status in intermediate uveitis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Review: uveitis and immunosuppressive drugs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

The possible impact of uveitis in blindness: a literature survey

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Cyclosporin a. Inhibition of experimental autoimmune uveitis in Lewis rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Functional properties of interphotoreceptor retinoid-binding protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Long-term efficacy and tolerance of tacrolimus for the treatment of uveitis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients with chronic plaque psoriasis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

The novel calcineurin inhibitor ISA247: a more potent immunosuppressant than cyclosporine in vitro.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Compared with cyclosporine, ISATX247 significantly prolongs renal-allograft survival in a nonhuman primate model

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Rodent models of experimental autoimmune uveitis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

Amelioration of accelerated collagen induced arthritis by a novel calcineurin inhibitor, ISA(TX)247.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

ISA(TX)247: a novel calcineurin inhibitor.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750843

ISATX247: a novel calcineurin inhibitor

2 September 2018

1 reference

12 December 2020

Ocular surface and tear functions after topical cyclosporine treatment in dry eye patients with chronic graft-versus-host disease

1 reference

12 December 2020

Cyclosporine a inhibits ATP net uptake of rat kidney mitochondria

1 reference

12 December 2020

Cyclosporine therapy for uveitis: long-term followup

1 reference

12 December 2020

Molecular analysis of resolving immune responses in uveitis

1 reference

12 December 2020

FR900506 (FK506) and 15-Deoxyspergualin (15-DSG) Modulate the Kinetics of Infiltrating Cells in Eyes with Experimental Autoimmune Uveoretinitis

1 reference

12 December 2020

Treatment of endogenous uveitis with cyclosporine A

1 reference

12 December 2020

Isolation and characterization of monkey interphotoreceptor retinoid-binding protein, a unique extracellular matrix component of the retina

1 reference

12 December 2020

Effects of cyclosporine and other immunosuppressive drugs on experimental autoimmune uveoretinitis in rats

1 reference

12 December 2020

In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates

1 reference

12 December 2020

Cyclosporine therapy for severe sight-threatening uveitis in children and adolescents

1 reference

12 December 2020

Pathology of experimental autoimmune uveoretinitis in mice

1 reference

12 December 2020

Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine

1 reference

12 December 2020

Combined cyclosporine and corticosteroid therapy for sight-threatening uveitis in Behçet's disease

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.08-1891

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19 August 2017

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19 August 2017

PubMed publication ID

18708627

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