IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts. (Q37370670)

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28 February 2020

title

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts (English)

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Jean-Laurent Casanova

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Cindy S Ma

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Jacinta Bustamante

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Stephanie Boisson-Dupuis

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Peter D Arkwright

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Anne Durandy

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Stuart Tangye

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Danielle T Avery

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Liliana Bezrodnik

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Chaim M Roifman

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Leen Moens

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Stephen Adelstein

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Lucinda J Berglund

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Elissa K Deenick

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Melanie Wong

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Rosa Bacchetta

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Harjit Dadi

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David A Fulcher

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John B Ziegler

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Joanne M Smart

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Masao Kobayashi

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Matthew C Cook

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language of work or name

English

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publication date

24 October 2013

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28 February 2020

volume

122

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issue

24

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page(s)

3940-3950

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Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

28 February 2020

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pERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulin

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26 June 2018

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2 September 2018

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IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

2 September 2018

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2 September 2018

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Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production.

2 September 2018

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Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage.

2 September 2018

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2 September 2018

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A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells.

2 September 2018

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Isotype Switching by Human B Cells Is Division-Associated and Regulated by Cytokines

2 September 2018

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12 December 2020

Demonstration of the involvement of interleukin 2 in the differentiation of Staphylococcus aureus Cowan I-stimulated B cells

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12 December 2020

Activated human B cells display a functional IL 2 receptor

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12 December 2020

Impaired antibody responses in the hyperimmunoglobulin E syndrome

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12 December 2020

Antibody responses to protein, polysaccharide, and ΦX174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome

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12 December 2020

Cytokine expression by germinal center cells

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12 December 2020

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation

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12 December 2020

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

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12 December 2020

10.1182/BLOOD-2013-06-506865

Identifiers

DOI

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