A quantitative model for age-dependent expression of the p16INK4a tumor suppressor (Q37377247)

20 August 2017

A quantitative model for age-dependent expression of the p16INK4a tumor suppressor (English)

1 reference

20 August 2017

4

1 reference

20 August 2017

Denis Tsygankov

1

0 references

Hanna K Sanoff

series ordinal

3

object named as

Hanna K Sanoff

1 reference

20 August 2017

Yan Liu

2

1 reference

20 August 2017

Timothy C Elston

series ordinal

5

1 reference

20 August 2017

language of work or name

English

0 references

publication date

14 September 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

20 August 2017

106

1 reference

20 August 2017

39

1 reference

20 August 2017

16562-16567

1 reference

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

The common biology of cancer and ageing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Genomewide association analysis of coronary artery disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

A common allele on chromosome 9 associated with coronary heart disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

A common variant on chromosome 9p21 affects the risk of myocardial infarction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

The regulation of INK4/ARF in cancer and aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

p16INK4a induces an age-dependent decline in islet regenerative potential

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

BRAFE600-associated senescence-like cell cycle arrest of human naevi

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Ink4a/Arf expression is a biomarker of aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Cancer and ageing: rival demons?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Cellular senescence in aging primates.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Ink4a/Arf expression is a biomarker of aging

2 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904405106

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904405106

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904405106

Delayed ageing through damage protection by the Arf/p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904405106

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757807

Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805338

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0904405106

1 reference

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

19805338

1 reference