Anti-acne agents attenuate FGFR2 signal transduction in acne (Q37395769)

20 August 2017

1 reference

title

Anti-acne agents attenuate FGFR2 signal transduction in acne (English)

1 reference

20 August 2017

Gerd Schmitz

2

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Bodo Melnik

series ordinal

1

object named as

Bodo C Melnik

1 reference

20 August 2017

Christos C Zouboulis

3

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PubMed ID

19225542

20 August 2017

language of work or name

English

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publication date

19 February 2009

1 reference

Journal of Investigative Dermatology

20 August 2017

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20 August 2017

129

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20 August 2017

8

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20 August 2017

1868-1877

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https://scigraph.springernature.com/pub.10.1038/jid.2009.8

20 August 2017

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cites work

Cytochrome p450: a target for drug development for skin diseases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Hedgehog signaling regulates sebaceous gland development

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Interleukin 1 immunoreactivity in sebaceous glands

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Endocytic pathways and biological effects induced by UVB-dependent or ligand-dependent activation of the keratinocyte growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Keratinocyte growth factor receptor ligands target the receptor to different intracellular pathways.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Successful acne management in Apert syndrome twins

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Messenger RNAs for the multifunctional cytokines interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor-alpha are present in adnexal tissues and in dermis of normal human skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Essential role for Sonic hedgehog during hair follicle morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Propionibacterium acnes stimulates pro-matrix metalloproteinase-2 expression through tumor necrosis factor-alpha in human dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Acne in Apert's syndrome: treatment with isotretinoin.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The endocrinology and developmental biology of the prostate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Keratinocyte growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Effects of azelaic acid on proliferation and ultrastructure of mouse keratinocytes in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Functional analysis of the human Sprouty2 gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Isotretinoin therapy for antibiotic-refractory acne in Apert's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Cellular signaling by fibroblast growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Towards dissecting the pathogenesis of retinoid-induced hair loss: all-trans retinoic acid induces premature hair follicle regression (catagen) by upregulation of transforming growth factor-beta2 in the dermal papilla

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Keratins and the keratinocyte activation cycle

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Azelaic acid and sebum excretion rate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

5 alpha-dihydrotestosterone formation is necessary for embryogenesis of the rat prostate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Isotretinoin treatment of acne in a patient with Apert syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Cytokinetic studies on the sebo-suppressive effect of drugs using the example of benzoyl peroxide

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The role of the chondrocyte in osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Comparative effect of isotretinoin and etretinate on acne and sebaceous gland secretion

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Management of acne: a report from a Global Alliance to Improve Outcomes in Acne.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Modeling acne in vitro

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Region-specific expression of androgen and growth factor pathway genes in the rat epididymis and the effects of dual 5alpha-reductase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Resolution of acne following therapy with an oral contraceptive in a patient with Apert syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Keratin expression in pilosebaceous epithelia in truncal skin of acne patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

All-trans retinoic acid compromises desmosome expression in human epidermis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Pro-inflammatory levels of interleukin-1 alpha-like bioactivity are present in the majority of open comedones in acne vulgaris.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Inflammatory events are involved in acne lesion initiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

13-cis retinoic acid and acne

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The treatment of acne with topical retinoids: one man's opinions

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Monoclonal antibody labeling for cytokeratins and filaggrin in the human pilosebaceous unit of normal, seborrhoeic and acne skin.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Inhibitory effects of 13-cis-retinoic acid on human sebaceous glands

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA micro

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Hormonal, cellular, and molecular control of prostatic development

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

A novel MAP kinase phosphatase is localised in the branchial arch region and tail tip of Xenopus embryos and is inducible by retinoic acid.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

FGFR2 signaling and the pathogenesis of acne

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Unilateral segmental acneiform naevus: a model disorder towards understanding fibroblast growth factor receptor 2 function in acne?

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Regulation of segmental patterning by retinoic acid signaling during Xenopus somitogenesis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Beneficial effect of 15% azelaic acid cream on acne vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

An ultrastructural study of the retention hyperkeratosis of experimentally induced comedones in rabbits: the effects of three comedolytics

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

SHP2 associates directly with tyrosine phosphorylated p90 (SNT) protein in FGF-stimulated cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Isotretinoin for acne in Apert syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

All-trans retinoic acid-induced hyaluronan production and hyperplasia are partly mediated by EGFR signaling in epidermal keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Antimitochondrial effect of saturated medium chain length (C8-C13) dicarboxylic acids

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Digital image analysis of microcomedones

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Sebaceous gland response in man to the administration of testosterone, delta-4-androstenedione, and dehydroisoandrosterone

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Fibroblast growth factors, their receptors and signaling

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Androgen regulation of prostate morphoregulatory gene expression: Fgf10-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Successful treatment of the acne of Apert syndrome with isotretinoin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Differential rates of conversion of testosterone to dihydrotestosterone in acne and in normal human skin--a possible pathogenic factor in acne

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

All-trans-retinoic acid and 13-cis-retinoic acid: pharmacokinetics and biological activity in different cell culture models of human keratinocytes.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Testosterone formation and metabolism during male sexual differentiation in the human embryo

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

On the role of transforming growth factor-beta in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Sonic hedgehog signaling is essential for hair development

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The effect of marked inhibition of sebum production with 13cis-retinoic acid on skin surface lipid composition

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Activity of 5-alpha-reductase and 17-beta-hydroxysteroid dehydrogenase in the infrainfundibulum of subjects with and without acne vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Effect of alpha-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the rat

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Proceedings: A radioimmunoassay for alpha-melanocyte-stimulating hormone in the rat

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Trans retinoic acid enhances the growth response of epidermal keratinocytes to epidermal growth factor and transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Gene array expression profiling in acne lesions reveals marked upregulation of genes involved in inflammation and matrix remodeling

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

13-cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Pharmacokinetic interactions between theophylline and other medication (Part I).

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Topical tretinoin in acne therapy

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Proopiomelanocortin peptides and sebogenesis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Melanocortin-5 receptor: a marker of human sebocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Treatment of acne with antiandrogens--an evidence-based review

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Frontiers in sebaceous gland biology and pathology

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

What is the pathogenesis of acne?

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Effects of 13-Cis-Retinoic Acid, All-Trans-Retinoic Acid, and Acitretin on the Proliferation, Lipid Synthesis and Keratin Expression of Cultured Human Sebocytes In Vitro

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95).

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

The human sebocyte culture model provides new insights into development and management of seborrhoea and acne

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.8

7 January 2021

Identifiers

DOI

10.1038/JID.2009.8

1 reference

20 August 2017

1 reference

PubMed ID

19225542