Lentiviral vectors for gene transfer into the spinal cord glial cells (Q37401091)

20 August 2017

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title

Lentiviral vectors for gene transfer into the spinal cord glial cells (English)

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20 August 2017

A Meunier

1

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PubMed ID

19242525

20 August 2017

M Pohl

series ordinal

2

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20 August 2017

26 February 2009

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20 August 2017

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20 August 2017

16

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20 August 2017

4

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20 August 2017

476-482

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https://scigraph.springernature.com/pub.10.1038/gt.2009.22

20 August 2017

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Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

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Chronic pain-induced astrocyte activation in the cingulate cortex with no change in neural or glial differentiation from neural stem cells in mice.

21 January 2018

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A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

21 January 2018

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An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

21 January 2018

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Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

21 January 2018

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Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10

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Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats

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Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain

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Gene delivery to the nervous system

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Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

21 January 2018

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Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery

21 January 2018

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Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses

21 January 2018

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Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins

21 January 2018

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Production and neurotropism of lentivirus vectors pseudotyped with lyssavirus envelope glycoproteins.

21 January 2018

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Transduction of human glial and neuronal tumor cells with different lentivirus vector pseudotypes.

21 January 2018

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In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins

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Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

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Effective gene therapy with nonintegrating lentiviral vectors

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Lentiviral vectors: optimization of packaging, transduction and gene expression

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The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.

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Characterization of lentiviral vector-mediated gene transfer in adult mouse brain

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Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF.

21 January 2018

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Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells.

21 January 2018

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Lentiviral-mediated targeted transgene expression in dorsal spinal cord glia: tool for the study of glial cell implication in mechanisms underlying chronic pain development.

21 January 2018

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Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

21 January 2018

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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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NF-kappaB as a therapeutic target in chronic inflammation: recent advances

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Do glial cells control pain?

21 January 2018

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Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation

21 January 2018

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Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats.

21 January 2018

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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

21 January 2018

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Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats

21 January 2018

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Enhancement of cell-specific transgene expression from a Tet-Off regulatory system using a transcriptional amplification strategy in the rat brain

21 January 2018

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Oxidative stress-inducible lentiviral vectors for gene therapy.

21 January 2018

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Silencing of human alpha-synuclein in vitro and in rat brain using lentiviral-mediated RNAi

21 January 2018

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Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

21 January 2018

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Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats.

21 January 2018

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Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions

21 January 2018

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Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour

21 January 2018

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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

21 January 2018

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Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells

21 January 2018

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7 January 2021

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.22

7 January 2021

Gene Delivery to the Nervous System: NINDS Workshop on Gene Delivery to the Nervous System Washington, DC, 12-13 November 2007

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https://api.crossref.org/works/10.1038%2FGT.2009.22

7 January 2021

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

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7 January 2021

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

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7 January 2021

Lentiviral-mediated Targeted NF-κB Blockade in Dorsal Spinal Cord Glia Attenuates Sciatic Nerve Injury-induced Neuropathic Pain in the Rat

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7 January 2021

Identifiers

DOI

10.1038/GT.2009.22

1 reference

PubMed ID

19242525

Dimensions Publication ID

20 August 2017

0 references

1 reference

PubMed ID

19242525