Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats. (Q44016790)

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23 November 2019

title

Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats (English)

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23 November 2019

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23 November 2019

author name string

Ellen Niederberger

2

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23 November 2019

Ronald Schmidt

3

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23 November 2019

Susanne Kunz

4

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23 November 2019

Hans Gühring

5

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23 November 2019

Olaf Ritzeler

6

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23 November 2019

Martin Michaelis

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23 November 2019

Gerd Geisslinger

8

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language of work or name

English

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publication date

1 February 2004

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23 November 2019

published in

Journal of Neuroscience

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23 November 2019

volume

24

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23 November 2019

issue

7

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23 November 2019

page(s)

1637-1645

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Local expression of inducible nitric oxide synthase in an animal model of neuropathic pain

23 November 2019

cites work

1 reference

12 December 2020

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

12 December 2020

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

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12 December 2020

The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior

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12 December 2020

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

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Activators and target genes of Rel/NF-kappaB transcription factors

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Aberrant rel/nfkb genes and activity in human cancer

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Activation of NF-kappaB by FADD, Casper, and caspase-8.

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Thiol-reactive metal compounds inhibit NF-kappa B activation by blocking I kappa B kinase

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Microglial proliferation in the spinal cord of aged rats with a sciatic nerve injury

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12 December 2020

Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis

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12 December 2020

Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide

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12 December 2020

Activation of the NF-kappaB pathway by caspase 8 and its homologs

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12 December 2020

Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin

1 reference

12 December 2020

Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen

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12 December 2020

Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

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12 December 2020

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

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12 December 2020

NF-kappaB in cancer: from innocent bystander to major culprit

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12 December 2020

The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats.

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12 December 2020

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells.

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12 December 2020

Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease

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12 December 2020

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

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12 December 2020

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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12 December 2020

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

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12 December 2020

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

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12 December 2020

Expression of c-fos and c-jun family genes after focal cerebral ischemia

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12 December 2020

Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

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12 December 2020

Inhibition of the DNA-binding activity of NF-kappa B by gold compounds in vitro

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12 December 2020

Inhibition of NF-kappa B by sodium salicylate and aspirin

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12 December 2020

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

1 reference

12 December 2020

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

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12 December 2020

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

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12 December 2020

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

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12 December 2020

Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

1 reference

12 December 2020

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

12 December 2020

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

1 reference

12 December 2020

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1 reference

12 December 2020

Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat.

1 reference

12 December 2020

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

12 December 2020

Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine

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12 December 2020

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

12 December 2020

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

1 reference

12 December 2020

Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression.

1 reference

12 December 2020

The NF-kappaB/Rel family of proteins mediates Abeta-induced neurotoxicity and glial activation.

1 reference

12 December 2020

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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12 December 2020

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

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12 December 2020

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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12 December 2020

Ca2+-mediated activation of c-Jun N-terminal kinase and nuclear factor kappa B by NMDA in cortical cell cultures.

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12 December 2020

Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.

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12 December 2020

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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12 December 2020

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

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12 December 2020

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

12 December 2020

Unilateral injection of calcitonin gene-related peptide (CGRP) induces bilateral oedema formation and release of CGRP-like immunoreactivity in the rat hindpaw

1 reference

12 December 2020

10.1523/JNEUROSCI.3118-03.2004

Identifiers

DOI

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23 November 2019

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