Cell death/proliferation roles for nc886, a non-coding RNA, in the protein kinase R pathway in cholangiocarcinoma (Q37407462)

20 August 2017

Cell death/proliferation roles for nc886, a non-coding RNA, in the protein kinase R pathway in cholangiocarcinoma (English)

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20 August 2017

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N Kunkeaw

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20 August 2017

S H Jeon

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K Lee

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B H Johnson

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S Tanasanvimon

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M Javle

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C Pairojkul

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Y Chamgramol

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W Wongfieng

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B Gong

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C Leelayuwat

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Y S Lee

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language of work or name

English

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publication date

27 August 2012

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32

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32

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3722-3731

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describes a project that uses

20 August 2017

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https://scigraph.springernature.com/pub.10.1038/onc.2012.382

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cites work

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Precursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity.

6 September 2017

1 reference

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6 September 2017

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NF-kappaB and cancer: how intimate is this relationship

6 September 2017

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Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis.

6 September 2017

1 reference

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Epstein-barr virus-induced expression of a novel human vault RNA

6 September 2017

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Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation

6 September 2017

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6 September 2017

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The dsRNA protein kinase PKR: virus and cell control

6 September 2017

1 reference

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Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis

6 September 2017

1 reference

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Coping with stress: eIF2 kinases and translational control

6 September 2017

1 reference

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Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

6 September 2017

1 reference

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

6 September 2017

1 reference

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Protein expression of double-stranded RNA-activated protein kinase in thyroid carcinomas: correlations with histologic types, pathologic parameters, and Ki-67 labeling

6 September 2017

1 reference

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MAPs and POEP of the roads from prokaryotic to eukaryotic kingdoms

6 September 2017

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Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cells

6 September 2017

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eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

6 September 2017

1 reference

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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

6 September 2017

1 reference

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Selective leukemia cell death by activation of the double-stranded RNA-dependent protein kinase PKR.

6 September 2017

1 reference

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PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

14 September 2017

1 reference

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14 September 2017

Evolution of vault RNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

Role of double-stranded RNA-activated protein kinase in human hematological malignancies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

Defective translational control facilitates vesicular stomatitis virus oncolysis

28 September 2017

1 reference

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Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2alpha in transformed cells

26 June 2018

1 reference

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Expression of the double-stranded RNA-dependent protein kinase (p68) in human breast tissues.

26 June 2018

1 reference

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Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.

26 June 2018

1 reference

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Uncovering the PKR pathway's potential for treatment of tumors.

26 June 2018

1 reference

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A point mutation in the RNA-binding domain I results in decrease of PKR activation in acute lymphoblastic leukemia.

2 September 2018

1 reference

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Loss of PKR activity in chronic lymphocytic leukemia.

2 September 2018

1 reference

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Protein kinase R is increased and is functional in hepatitis C virus-related hepatocellular carcinoma

2 September 2018

1 reference

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Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR).

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3869796

Hepatitis C virus and alcohol: same mitotic targets but different signaling pathways

2 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Up-regulation of annexin A2 in cholangiocarcinoma caused by Opisthorchis viverrini and its implication as a prognostic marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Levels, phosphorylation status and cellular localization of translational factor eIF2 in gastrointestinal carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Characterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.382

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cel

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22926522

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.382

1 reference

20 August 2017

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20 August 2017

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