Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis (Q37411011)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24344181%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis (English)

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3 March 2020

3

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3 March 2020

Elsa Logarinho

4

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3 March 2020

Helder Maiato

6

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3 March 2020

author name string

Nina Schweizer

1

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3 March 2020

Cristina Ferrás

2

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3 March 2020

Iain M Cheeseman

5

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3 March 2020

language of work or name

English

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publication date

1 December 2013

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3 March 2020

published in

Journal of Cell Biology

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3 March 2020

volume

203

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3 March 2020

issue

6

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3 March 2020

page(s)

883-893

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Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting

3 March 2020

cites work

1 reference

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Functional interaction between the Arabidopsis orthologs of spindle assembly checkpoint proteins MAD1 and MAD2 and the nucleoporin NUA.

6 September 2017

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Structure of the mitotic checkpoint complex

6 September 2017

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Localization of nucleoporin Tpr to the nuclear pore complex is essential for Tpr mediated regulation of the export of unspliced RNA.

6 September 2017

1 reference

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Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC)

6 September 2017

1 reference

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Silencing nuclear pore protein Tpr elicits a senescent-like phenotype in cancer cells

6 September 2017

1 reference

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Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint

6 September 2017

1 reference

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The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway

6 September 2017

1 reference

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Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis

6 September 2017

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Optimization of formaldehyde cross-linking for protein interaction analysis of non-tagged integrin beta1

6 September 2017

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Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.

6 September 2017

1 reference

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Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

6 September 2017

1 reference

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Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex

6 September 2017

1 reference

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Chemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosis

6 September 2017

1 reference

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Systematic analysis of human protein complexes identifies chromosome segregation proteins

6 September 2017

1 reference

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Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator

6 September 2017

1 reference

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Mlp1 acts as a mitotic scaffold to spatially regulate spindle assembly checkpoint proteins in Aspergillus nidulans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

6 September 2017

1 reference

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The spindle-assembly checkpoint in space and time

6 September 2017

1 reference

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

6 September 2017

1 reference

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The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing

6 September 2017

1 reference

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Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export

6 September 2017

1 reference

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The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint

6 September 2017

1 reference

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Spindle checkpoint requires Mad1-bound and Mad1-free Mad2.

6 September 2017

1 reference

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Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint

6 September 2017

1 reference

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Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

6 September 2017

1 reference

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Large-scale analysis of the yeast proteome by multidimensional protein identification technology

6 September 2017

1 reference

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Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase

6 September 2017

1 reference

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The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins

6 September 2017

1 reference

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NUCLEAR PORE ANCHOR, the Arabidopsis homolog of Tpr/Mlp1/Mlp2/megator, is involved in mRNA export and SUMO homeostasis and affects diverse aspects of plant development.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

The Mad2 spindle checkpoint protein has two distinct natively folded states.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871433

Control of localization of a spindle checkpoint protein, Mad2, in fission yeast

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24344181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201309076

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release_ediqmecrcraqjiyvr2df5svfyu

3 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ediqmecrcraqjiyvr2df5svfyu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24344181%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

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