A global suppressor motif for p53 cancer mutants (Q37415505)

20 August 2017

A global suppressor motif for p53 cancer mutants (English)

1 reference

20 August 2017

3

Hua Qian

1 reference

20 August 2017

Timothy E Baroni

1

1 reference

20 August 2017

Ting Wang

2

1 reference

20 August 2017

Lawrence R Dearth

4

1 reference

20 August 2017

Lan N Truong

5

1 reference

20 August 2017

Jue Zeng

6

1 reference

20 August 2017

Alec E Denes

7

1 reference

20 August 2017

Stephanie W Chen

8

1 reference

20 August 2017

Rainer K Brachmann

9

1 reference

20 August 2017

language of work or name

English

0 references

publication date

22 March 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

20 August 2017

101

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20 August 2017

14

1 reference

20 August 2017

4930-4935

1 reference

Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

The UMD-p53 database: new mutations and analysis tools

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Therapeutic exploitation of the p53 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Rescuing the function of mutant p53.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

hADA3 is required for p53 activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

6 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

p53-oriented cancer therapies: current progress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Isolation of a novel GPI-anchored gene specifically regulated by p53; correlation between its expression and anti-cancer drug sensitivity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

WAF1, a potential mediator of p53 tumor suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Genetic analysis of staphylococcal nuclease: identification of three intragenic "global" suppressors of nuclease-minus mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

PCR-based random mutagenesis using manganese and reduced dNTP concentration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=387351

The IARC TP53 database: new online mutation analysis and recommendations to users

26 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Rescue of mutant p53 transcription function by ellipticine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Pharmacological rescue of mutant p53 conformation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Efficient PCR-based random mutagenesis of sub-genic (100 bp) DNA fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

Structure-based rescue of common tumor-derived p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401162101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0401162101

1 reference

20 August 2017

0 references

1 reference

20 August 2017

1 reference