Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site. (Q37415685)

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English	Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site.	scientific article

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1 March 2020

Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site (English)

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1 March 2020

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1 March 2020

Susan T Sharfstein

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1 March 2020

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Guoyun Li

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1 March 2020

Bo Yang

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1 March 2020

Xue Zhao

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1 March 2020

Jong Youn Baik

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1 March 2020

Trent R Gemmill

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1 March 2020

Robert J Linhardt

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18 November 2013

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1 March 2020

Journal of Biological Chemistry

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1 March 2020

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1 March 2020

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1 March 2020

37308-37318

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1 March 2020

Structural characterization of pharmaceutical heparins prepared from different animal tissues

1 reference

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6 September 2017

An 'omics approach towards CHO cell engineering.

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6 September 2017

Microscale separation of heparosan, heparan sulfate, and heparin

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6 September 2017

Heparin biosynthesis

1 reference

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6 September 2017

Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin

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6 September 2017

Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin

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6 September 2017

Disaccharide analysis of glycosaminoglycan mixtures by ultra-high-performance liquid chromatography-mass spectrometry

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6 September 2017

Structural characterization of heparins from different commercial sources

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6 September 2017

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

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6 September 2017

Anticoagulant heparan sulfate to not clot--or not?

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6 September 2017

E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor

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6 September 2017

Heparan sulfate proteoglycans: structure, protein interactions and cell signaling

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6 September 2017

Lessons learned from the contamination of heparin

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6 September 2017

2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis

1 reference

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6 September 2017

Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation

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6 September 2017

Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation

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6 September 2017

Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality

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6 September 2017

Biosynthesis of chondroitin and heparan sulfate in chinese hamster ovary cells depends on xylosyltransferase II.

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6 September 2017

Synthesis of Anticoagulantly Active Heparan Sulfate Proteoglycans by Glomerular Epithelial Cells Involves Multiple 3-O-Sulfotransferase Isoforms and a Limiting Precursor Pool

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6 September 2017

Characterization of the structure of antithrombin-binding heparan sulfate generated by heparan sulfate 3-O-sulfotransferase 5.

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6 September 2017

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

1 reference

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6 September 2017

Heparan Sulfate Core Proteins in Cell-Cell Signaling

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6 September 2017

Mice deficient in heparan sulfate 3-O-sulfotransferase-1: Normal hemostasis with unexpected perinatal phenotypes

2 references

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6 September 2017

https://api.crossref.org/works/10.1074%2FJBC.M113.519033

21 January 2018

Oligosaccharide Library-based Assessment of Heparan Sulfate 6-O-Sulfotransferase Substrate Specificity

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6 September 2017

Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases

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6 September 2017

Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes

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6 September 2017

Order out of chaos: assembly of ligand binding sites in heparan sulfate

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6 September 2017

Molecular diversity of heparan sulfate

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6 September 2017

The effect of precursor structures on the action of glucosaminyl 3-O-sulfotransferase-1 and the biosynthesis of anticoagulant heparan sulfate

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6 September 2017

Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4

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6 September 2017

The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine

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6 September 2017

Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

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6 September 2017

Heparin is essential for the storage of specific granule proteases in mast cells

1 reference

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6 September 2017

Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities

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6 September 2017

Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci

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6 September 2017

Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family

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6 September 2017

Animal cell mutants defective in glycosaminoglycan biosynthesis

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6 September 2017

Stable heparin-producing cell lines derived from the Furth murine mastocytoma

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6 September 2017

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase

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6 September 2017

CHO glycosylation mutants: proteoglycans

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14 September 2017

6-O-sulfotransferase-1 represents a critical enzyme in the anticoagulant heparan sulfate biosynthetic pathway

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28 September 2017

Substrate specificity of the heparan sulfate hexuronic acid 2-O-sulfotransferase

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28 September 2017

Influence of core protein sequence on glycosaminoglycan assembly

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28 September 2017

Expression of the mouse mastocytoma glucosaminyl N-deacetylase/ N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate

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28 September 2017

Asparagine 405 of heparin lyase II prevents the cleavage of glycosidic linkages proximate to a 3-O-sulfoglucosamine residue

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26 June 2018

Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line.

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26 June 2018

cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin.

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26 June 2018

Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I.

1 reference

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26 June 2018

Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin

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2 September 2018

Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases

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2 September 2018

Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells

1 reference

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2 September 2018

Identification and expression in mouse of two heparan sulfate glucosaminyl N-deacetylase/N-sulfotransferase genes

1 reference

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2 September 2018

Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate D-glucuronosyl 5-epimerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24247246

12 December 2020

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10.1074/JBC.M113.519033

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Europe PubMed Central

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1 March 2020

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1 March 2020

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Europe PubMed Central

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1 March 2020

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