Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes. (Q37429329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19741158%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes (English)

1 reference

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7 February 2020

0 references

3

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7 February 2020

author name string

Rajesh Ramakrishnan

series ordinal

1

1 reference

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7 February 2020

Eugene C Dow

series ordinal

2

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7 February 2020

publication date

10 September 2009

1 reference

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Journal of Leukocyte Biology

7 February 2020

published in

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7 February 2020

volume

86

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issue

6

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page(s)

1345-1350

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describes a project that uses

7 February 2020

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2780919/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop

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Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event

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The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

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PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

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Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription

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Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells

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Controlling the elongation phase of transcription with P-TEFb

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Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality

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Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation

23 August 2017

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Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages

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Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo

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Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines

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The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions.

23 August 2017

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Diversity of conformational states and changes within the EF-hand protein superfamily

23 August 2017

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Tat-associated kinase, TAK, activity is regulated by distinct mechanisms in peripheral blood lymphocytes and promonocytic cell lines

23 August 2017

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A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.

23 August 2017

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Protein kinase activation loop autophosphorylation in cis: overcoming a Catch-22 situation

23 August 2017

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Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.

2 September 2018

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Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19741158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential localization and expression of the Cdk9 42k and 55k isoforms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19741158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1189/JLB.0509309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19741158%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19741158%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference