Sodium channel mutations and arrhythmias (Q37450777)

20 August 2017

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title

Sodium channel mutations and arrhythmias (English)

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20 August 2017

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Yanfei Ruan

1

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20 August 2017

Nian Liu

series ordinal

2

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20 August 2017

Silvia G Priori

series ordinal

3

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20 August 2017

language of work or name

English

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publication date

1 May 2009

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Nature Reviews Cardiology

20 August 2017

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20 August 2017

6

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20 August 2017

5

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20 August 2017

337-348

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https://scigraph.springernature.com/pub.10.1038/nrcardio.2009.44

20 August 2017

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cites work

Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Enhanced Na(+) channel intermediate inactivation in Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Prevalence of paroxysmal atrial fibrillation in Brugada syndrome: a case series and a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A single Na(+) channel mutation causing both long-QT and Brugada syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Congenital long-QT syndrome caused by a novel mutation in a conserved acidic domain of the cardiac Na+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: A prospective evaluation of 52 families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Cardiac conduction defects associate with mutations in SCN5A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Compound heterozygosity for mutations (W156X and R225W) in SCN5A associated with severe cardiac conduction disturbances and degenerative changes in the conduction system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Cardiac Sodium Channel Diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Inherited disorders of voltage-gated sodium channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mutation-specific pharmacology of the long QT syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Gene-specific therapy for inherited arrhythmogenic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

The cardiac sodium channel: gating function and molecular pharmacology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Molecular mechanism for an inherited cardiac arrhythmia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Yield of genetic screening in inherited cardiac channelopathies: how to prioritize access to genetic testing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A sodium channel pore mutation causing Brugada syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Trafficking and functional expression of cardiac Na+ channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Pharmacological rescue of mutant ion channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

SCN5A mutation (T1620M) causing Brugada syndrome exhibits different phenotypes when expressed in Xenopus oocytes and mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Electrophysiological basis and genetics of Brugada syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Heterogeneity and cardiac arrhythmias: an overview.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A sodium-channel mutation causes isolated cardiac conduction disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

SCN5A and sinoatrial node pacemaker function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mapping a cardiomyopathy locus to chromosome 3p22-p25.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

The Elusive Link Between LQT3 and Brugada Syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Natural history of Brugada syndrome: insights for risk stratification and management

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

SCN5A overlap syndromes: no end to disease complexity?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Inherited arrhythmogenic diseases: the complexity beyond monogenic disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiolo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Gating Properties of SCN5A Mutations and the Response to Mexiletine in Long-QT Syndrome Type 3 Patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A cardiac sodium channel mutation identified in Brugada syndrome associated with atrial standstill

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

A novel C-terminal truncation SCN5A mutation from a patient with sick sinus syndrome, conduction disorder and ventricular tachycardia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.44

Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19377496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19377496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRCARDIO.2009.44

1 reference

Dimensions Publication ID

20 August 2017

0 references

1 reference