Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy. (Q37475156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367117%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy (English)

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3 March 2020

4

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3 March 2020

author name string

Seamus R Morrone

1

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3 March 2020

Tao Wang

2

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3 March 2020

Leeza M Constantoulakis

3

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3 March 2020

Michael J Delannoy

5

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3 March 2020

Jungsan Sohn

6

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3 March 2020

language of work or name

English

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publication date

23 December 2013

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Proceedings of the National Academy of Sciences of the United States of America

3 March 2020

published in

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3 March 2020

volume

111

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3 March 2020

page(s)

E62-71

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3 March 2020

issue

1

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Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion

3 March 2020

cites work

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Nuclear DNA sensor IFI16 as circulating protein in autoimmune diseases is a signal of damage that impairs endothelial cells through high-affinity membrane binding.

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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MDA5 assembles into a polar helical filament on dsRNA.

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

23 August 2017

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MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

23 August 2017

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The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication

23 August 2017

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23 August 2017

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Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization

23 August 2017

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IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

23 August 2017

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IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

23 August 2017

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Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes.

6 September 2017

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Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection

14 September 2017

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14 September 2017

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During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes

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12 December 2020

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12 December 2020

Role of the Interferon-Inducible Gene IFI16 in the Etiopathogenesis of Systemic Autoimmune Disorders

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1313577111

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367117%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24367117%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

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