Pig-to-nonhuman primate islet xenotransplantation (Q37475745)

20 August 2017

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title

Pig-to-nonhuman primate islet xenotransplantation (English)

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20 August 2017

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Bernhard J Hering

1

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PubMed ID

19427901

20 August 2017

Niketa Walawalkar

series ordinal

2

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20 August 2017

7 May 2009

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20 August 2017

Transplant Immunology

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20 August 2017

21

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20 August 2017

2

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20 August 2017

81-86

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Pig-to-nonhuman primate islet xenotransplantation: a review of current problems

20 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Islet xenotransplantation: current status of preclinical studies in the pig-to-nonhuman primate model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Pig islet xenotransplantation into non-human primate model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

International trial of the Edmonton protocol for islet transplantation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplantation: current developments and future directions; the future of clinical islet transplantation as a cure for diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

The 30-year natural history of type 1 diabetes complications: the Pittsburgh Epidemiology of Diabetes Complications Study experience

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Position Paper of the Ethics Committee of the International Xenotransplantation Association

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Immunotherapy with nondepleting anti-CD4 monoclonal antibodies but not CD28 antagonists protects islet graft in spontaneously diabetic nod mice from autoimmune destruction and allogeneic and xenogeneic graft rejection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Pig islet xenografts are resistant to autoimmune destruction by non-obese diabetic recipients after anti-CD4 treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

The immune regulatory effect of apoptotic cells and exosomes on dendritic cells: its impact on transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

What makes clinical research ethical?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Xenotransplantation: infectious risk revisited

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Position paper of the Ethics Committee of the International Xenotransplantation Association

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Xenotransplantation of pig islets into Mexican children: were the fundamental ethical requirements to proceed with such a study really met?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplant tolerance in non-human primates: progress, current challenges and unmet needs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Rapid failure of pig islet transplantation in non human primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

T-cell-specific immunosuppression results in more than 53 days survival of porcine islets of langerhans in the monkey.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Reversal of diabetes in non-immunosuppressed rhesus macaques by intraportal porcine islet xenografts precedes acute cellular rejection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: proof of concept

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplantation of normal and DAF-transgenic fetal pig pancreas into cynomolgus monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Fetal islet xenotransplantation in rodents and primates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: an immunohistochemical study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplantation of micro- and macroencapsulated piglet islets into mice and monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplantation of neonatal porcine islets and sertoli cells into nonimmunosuppressed nonhuman primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Post-transplant upregulation of chemokine messenger RNA in non-human primate recipients of intraportal pig islet xenografts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Survival of adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) in cynomolgus monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Engraftment of adult porcine islet xenografts in diabetic nonhuman primates through targeting of costimulation pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Reduction of early graft loss after intraportal porcine islet transplantation in monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: implications for translation into clinical practice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Intraperitoneal alginate-encapsulated neonatal porcine islets in a placebo-controlled study with 16 diabetic cynomolgus primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Long-term engraftment following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic rhesus macaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Transplantation of mouse pancreatic islets into primates--in vivo and in vitro evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Regeneration of abdominal wall musculofascial defects by a human acellular collagen matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

The instant blood-mediated inflammatory reaction in xenogeneic islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Immunosuppressive protocols for pig-to-human islet transplantation: lessons from pre-clinical non-human primate models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

CD40/CD154 interactions at the interface of tolerance and immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Tolerogenic dendritic cells and the quest for transplant tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Mitomycin-C treatment followed by culture produces long-term survival of islet xenografts in a rat-to mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Functional and histological evaluation of transplanted pancreatic islets immunoprotected by PEGylation and cyclosporine for 1 year

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Layer-by-layer assembly of a conformal nanothin PEG coating for intraportal islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Extracellular matrix protein-coated scaffolds promote the reversal of diabetes after extrahepatic islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Growth factor delivery from self-assembling nanofibers to facilitate islet transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2009.05.001

10.1016/J.TRIM.2009.05.001

7 January 2021

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19427901