Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. (Q37477571)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19815667%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs (English)

1 reference

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9 February 2020

0 references

1

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9 February 2020

Youxian Li

5

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9 February 2020

author name string

Renping Qiao

2

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9 February 2020

Deyao Zhao

3

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9 February 2020

Tong Zhang

4

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9 February 2020

Fan Yi

6

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9 February 2020

Fangfang Lai

7

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9 February 2020

Junmei Hong

8

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9 February 2020

Xianfeng Ding

9

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9 February 2020

Zhenjun Yang

10

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9 February 2020

Lihe Zhang

11

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9 February 2020

Quan Du

12

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9 February 2020

Zicai Liang

13

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9 February 2020

language of work or name

English

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publication date

1 December 2009

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9 February 2020

published in

Nucleic Acids Research

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9 February 2020

volume

37

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9 February 2020

issue

22

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9 February 2020

page(s)

7560-7569

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The promises and pitfalls of RNA-interference-based therapeutics

9 February 2020

cites work

1 reference

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On the road to reading the RNA-interference code

23 August 2017

1 reference

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Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

23 August 2017

1 reference

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Structure of the guide-strand-containing argonaute silencing complex

23 August 2017

1 reference

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Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.

23 August 2017

1 reference

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Analysis of siRNA specificity on targets with double-nucleotide mismatches

23 August 2017

1 reference

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Interfering with disease: a progress report on siRNA-based therapeutics

23 August 2017

1 reference

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Designing siRNA that distinguish between genes that differ by a single nucleotide

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Determinants of specific RNA interference-mediated silencing of human beta-globin alleles differing by a single nucleotide polymorphism

23 August 2017

1 reference

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A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

"siRNAs and miRNAs": a meeting report on RNA silencing.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

High frequency of mutations of the PIK3CA gene in human cancers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells

23 August 2017

1 reference

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Allele-specific silencing of dominant disease genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Expression profiling reveals off-target gene regulation by RNAi

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

siRNAs can function as miRNAs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

23 August 2017

1 reference

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Many commonly used siRNAs risk off-target activity

23 August 2017

1 reference

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

14 September 2017

1 reference

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Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

RNAi in human cells: basic structural and functional features of small interfering RNA.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794185

Validating siRNA using a reporter made from synthetic DNA oligonucleotides

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19815667

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKP835

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19815667%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19815667%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference