Optimizing pediatric dosing: a developmental pharmacologic approach (Q37498862)

20 August 2017

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title

Optimizing pediatric dosing: a developmental pharmacologic approach (English)

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20 August 2017

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Gail D Anderson

1

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20 August 2017

Anne M Lynn

series ordinal

2

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20 August 2017

language of work or name

English

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publication date

1 June 2009

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20 August 2017

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20 August 2017

volume

29

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20 August 2017

issue

6

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20 August 2017

page(s)

680-690

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Modelling approaches to dose estimation in children

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Guidelines on paediatric dosing on the basis of developmental physiology and pharmacokinetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Mechanism-based concepts of size and maturity in pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

A mechanistic approach to antiepileptic drug interactions

21 January 2018

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https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Inhibition-based metabolic drug-drug interactions: predictions from in vitro data

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Application of routine monitoring data for determination of the population pharmacokinetics and enteral bioavailability of phenytoin in neonates and infants with seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Role of transport proteins in drug absorption, distribution and excretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and metabolism of oral midazolam in preterm infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Involvement of multiple efflux transporters in hepatic disposition of fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Impact of ontogeny on linezolid disposition in neonates and infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Children versus adults: pharmacokinetic and adverse-effect differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Clinical significance of pharmacokinetic models of hepatic elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Maturation of caffeine elimination in infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Clozapine pharmacokinetics in children and adolescents with childhood-onset schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Steady-state pharmacokinetics of bupropion SR in juvenile patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Single-dose pharmacokinetics of bupropion in adolescents: effects of smoking status and gender

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Developmental expression of human hepatic CYP2C9 and CYP2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Developmental changes in pharmacokinetics and pharmacodynamics of warfarin enantiomers in Japanese children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Single-dose and steady-state pharmacokinetics of celecoxib in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetic-pharmacodynamic study of oral lansoprazole in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Omeprazole disposition in children following single-dose administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of omeprazole in healthy adults and in children with gastroesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and pharmacodynamics of lansoprazole in children 13 to 24 months old with gastroesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Atomoxetine pharmacokinetics in children and adolescents with attention deficit hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Fluoxetine pharmacokinetics in pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Plasma pharmacokinetic characteristics of risperidone and their relationship to saliva concentrations in children with psychiatric or neurodevelopmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The human hepatic cytochromes P450 involved in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Development of CYP2D6 and CYP3A4 in the first year of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Cisapride disposition in neonates and infants: in vivo reflection of cytochrome P450 3A4 ontogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The single-dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Effect of age, ethnicity, and glucocorticoid use on tacrolimus pharmacokinetics in pediatric renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Influence of age and comedication on steady-state clonazepam serum level-dose ratios in Japanese epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Population analysis of weight-, age-, and sex-related differences in the pharmacokinetics of lopinavir in children from birth to 18 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and pharmacodynamics of saquinavir in pediatric patients with human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of zidovudine and lamivudine in neonates following coadministration of oral doses every 12 hours

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

A study of conjugation and drug elimination in the human neonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of a 24-hour intravenous ketoprofen infusion in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Isoniazid pharmacokinetics in children according to acetylator phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Changes in plasma protein binding have little clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and efficacy of ropivacaine for continuous epidural infusion in neonates and infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Stable plasma concentrations of unbound ropivacaine during postoperative epidural infusion for 24-72 hours in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Gestational age and birth weight effects on plasma clearance of fentanyl in newborn infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and metabolism of intravenous midazolam in preterm infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Maturational pharmacokinetics of single intravenous bolus of propofol

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Inter-individual variability in propofol pharmacokinetics in preterm and term neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of alfentanil in children undergoing surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The pharmacokinetics of the intravenous formulation of fentanyl citrate administered orally in children undergoing general anesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of transdermal fentanyl in the peri-operative period in young children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of a single bolus of propofol in chinese children of different ages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of valproic acid in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of oral acyclovir in neonates and in infants: a population analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Cellular and molecular aspects of drug transport in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The pharmacokinetics of enalapril in children and infants with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Morphine clearance and effects in newborn infants in relation to gestational age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Morphine metabolism in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Determination of population pharmacokinetic parameters for amikacin in neonates using mixed-effect models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Cefdinir pharmacokinetics and tolerability in children receiving 25 mg/kg once daily

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Once-daily versus twice-daily dosing of digoxin in the pediatric age group

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Pharmacokinetics of famotidine in infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Estimation of gentamicin clearance and volume of distribution in neonates and young children

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Population pharmacokinetics and relationship between demographic and clinical variables and pharmacokinetics of gentamicin in neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Population pharmacokinetics and pharmacodynamics of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Extended-interval dosing of tobramycin in neonates: implications for therapeutic drug monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Target concentration intervention is needed for tobramycin dosing in paediatric patients with cystic fibrosis--a population pharmacokinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

The influences of renal function and maturation on vancomycin elimination in newborns and infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

Vancomycin pharmacokinetics and Bayesian estimation in pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1592%2FPHCO.29.6.680

21 January 2018

Identifiers

DOI

10.1592/PHCO.29.6.680

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20 August 2017

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