Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. (Q37500513)

20 August 2017

Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. (English)

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20 August 2017

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Mauro Santibanez-Korev

series ordinal

3

object named as

Mauro Santibanez-Koref

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20 August 2017

Madhushika Ratnayake

1

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20 August 2017

Frank Plöger

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2

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20 August 2017

John Loughlin

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4

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20 August 2017

language of work or name

English

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publication date

21 January 2014

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20 August 2017

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20 August 2017

9

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20 August 2017

1

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20 August 2017

e86590

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Creative Commons Attribution 4.0 International

20 August 2017

start time

21 January 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Growth differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy

23 August 2017

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Controlled spatial and conformational display of immobilised bone morphogenetic protein-2 and osteopontin signalling motifs regulates osteoblast adhesion and differentiation in vitro

23 August 2017

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Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

23 August 2017

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Therapeutic effects of adenovirus-mediated growth and differentiation factor-5 in a mice disc degeneration model induced by annulus needle puncture

23 August 2017

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Multiple effects of GDF-5 deficiency on skeletal tissues: implications for therapeutic bioengineering

23 August 2017

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Cartilage-derived morphogenetic protein-1 and -2 are endogenously expressed in healthy and osteoarthritic human articular chondrocytes and stimulate matrix synthesis

23 August 2017

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Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta

23 August 2017

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TGF-beta signal transduction

23 August 2017

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Cartilage-derived morphogenetic proteins and osteogenic protein-1 differentially regulate osteogenesis

23 August 2017

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Cartilage-derived morphogenetic protein-1

23 August 2017

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Mutations in CDMP1 cause autosomal dominant brachydactyly type C

23 August 2017

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The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

23 August 2017

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Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5

23 August 2017

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Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2.

23 August 2017

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Intervertebral disk repair by protein, gene, or cell injection: a framework for rehabilitation-focused biologics in the spine

6 September 2017

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Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

6 September 2017

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Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

14 September 2017

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The effect of two point mutations in GDF-5 on ectopic bone formation in a beta-tricalciumphosphate scaffold

26 June 2018

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Effects induced by BMPS in cultures of human articular chondrocytes: comparative studies

2 September 2018

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A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis

2 September 2018

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In vivo growth factor treatment of degenerated intervertebral discs

2 September 2018

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Effects of growth differentiation factor-5 on the intervertebral disc--in vitro bovine study and in vivo rabbit disc degeneration model study

2 September 2018

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12 December 2020

Adenovirus-Mediated Gene Transfer of Growth and Differentiation Factor-5 into Tenocytes and the Healing Rat Achilles Tendon

1 reference

12 December 2020

An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

1 reference

12 December 2020

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

1 reference

12 December 2020

Expression of bone morphogenetic proteins, cartilage-derived morphogenetic proteins and related receptors in normal and osteoarthritic human articular cartilage

1 reference

12 December 2020

GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

1 reference

12 December 2020

Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease

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12 December 2020

A comparative dose-response study of cartilage-derived morphogenetic protein (CDMP)-1, -2 and -3 for tendon healing in rats

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12 December 2020

Growth factor responsiveness of human articular chondrocytes in aging and development

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12 December 2020

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

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12 December 2020

10.1371/JOURNAL.PONE.0086590

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DOI

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20 August 2017

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20 August 2017

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