Epidermal barrier dysfunction in atopic dermatitis. (Q37507508)

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30 January 2020

review article

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title

Epidermal barrier dysfunction in atopic dermatitis (English)

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30 January 2020

1

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30 January 2020

Simon G Danby

2

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30 January 2020

Richard H. Guy

7

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30 January 2020

author name string

Yiannis Vasilopoulos

3

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30 January 2020

Jonathan Hadgraft

4

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30 January 2020

Majella E Lane

5

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30 January 2020

Manar Moustafa

6

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30 January 2020

Alice L Macgowan

8

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30 January 2020

Rachid Tazi-Ahnini

9

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30 January 2020

Simon J Ward

10

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30 January 2020

language of work or name

English

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publication date

4 June 2009

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Journal of Investigative Dermatology

30 January 2020

published in

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30 January 2020

volume

129

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30 January 2020

issue

8

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30 January 2020

page(s)

1892-1908

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https://scigraph.springernature.com/pub.10.1038/jid.2009.133

30 January 2020

exact match

0 references

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Null Mutations in the Filaggrin Gene (FLG) Determine Major Susceptibility to Early-Onset Atopic Dermatitis that Persists into Adulthood

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NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging

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Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure

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A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation

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A proteolytic cascade of kallikreins in the stratum corneum

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7 January 2021

Filaggrin null mutations and childhood atopic eczema: A population-based case-control study

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The skin barrier, atopic dermatitis and allergy: a role for Langerhans cells?

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7 January 2021

The cornified envelope: a model of cell death in the skin

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Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

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Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity

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7 January 2021

Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation

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7 January 2021

Exposure to house dust mites in homes of people with atopic dermatitis

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7 January 2021

Comparison of parent knowledge, therapy utilization and severity of atopic eczema before and after explanation and demonstration of topical therapies by a specialist dermatology nurse.

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7 January 2021

New perspectives on epidermal barrier dysfunction in atopic dermatitis: gene-environment interactions.

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7 January 2021

Percutaneous absorption. Regional variations and the effect of hydration and epidermal stripping

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7 January 2021

Atopic dermatitis: a disease caused by innate immune defects?

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7 January 2021

Purified Der p1 and p2 patch tests in patients with atopic dermatitis: evidence for both allergenicity and proteolytic irritancy.

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7 January 2021

Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2

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7 January 2021

trans-4-(Aminomethyl)cyclohexane carboxylic acid (T-AMCHA), an anti-fibrinolytic agent, accelerates barrier recovery and prevents the epidermal hyperplasia induced by epidermal injury in hairless mice and humans.

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7 January 2021

Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: implication for seasonal exacerbations of inflammatory dermatoses.

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7 January 2021

LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction

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7 January 2021

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

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7 January 2021

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

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7 January 2021

Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children

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7 January 2021

Purification and preliminary characterization of stratum corneum chymotryptic enzyme: a proteinase that may be involved in desquamation

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7 January 2021

A chymotrypsin-like proteinase that may be involved in desquamation in plantar stratum corneum

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7 January 2021

Loss-of-function Variants of the Filaggrin Gene are Associated with Atopic Eczema and Associated Phenotypes in Swedish Families

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7 January 2021

Stratum corneum tryptic enzyme in normal epidermis: a missing link in the desquamation process?

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7 January 2021

The expression of stratum corneum chymotryptic enzyme in human anagen hair follicles: further evidence for its involvement in desquamation-like processes.

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7 January 2021

Epidermal lipids, barrier function, and desquamation

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7 January 2021

The epidermal permeability barrier: from the early days at Harvard to emerging concepts

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7 January 2021

Modulations in epidermal calcium regulate the expression of differentiation-specific markers

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7 January 2021

Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin

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7 January 2021

Eczema and infant diet

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7 January 2021

How atopic is atopic dermatitis?

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7 January 2021

Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity

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7 January 2021

Functional consequences of a neutral pH in neonatal rat stratum corneum

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7 January 2021

Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation.

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7 January 2021

A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities

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7 January 2021

Stratum corneum lipid removal by surfactants: relation to in vivo irritation

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7 January 2021

Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

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7 January 2021

Stratum corneum structure and function correlates with phenotype in psoriasis

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7 January 2021

The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption.

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7 January 2021

Expression cloning of human corneodesmosin proves its identity with the product of the S gene and allows improved characterization of its processing during keratinocyte differentiation

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Serine protease signaling of epidermal permeability barrier homeostasis

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7 January 2021

Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Immunocytochemical evidence for a possible role of cross-linked keratinocyte envelopes in stratum corneum cohesion.

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Abnormalities in clinically normal skin--a possible explanation of the 'angry back syndrome'

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7 January 2021

Epidermal overexpression of stratum corneum chymotryptic enzyme in mice: a model for chronic itchy dermatitis

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7 January 2021

High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis

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7 January 2021

Cyclosporin for severe childhood atopic dermatitis: short course versus continuous therapy.

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7 January 2021

On the role of the epidermal differentiation complex in ichthyosis vulgaris, atopic dermatitis and psoriasis

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7 January 2021

Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function

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7 January 2021

Effects of dermatitis, stripping, and steroids on the morphology of corneocytes. A new bioassay

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7 January 2021

Role of endogenous cathepsin D-like and chymotrypsin-like proteolysis in human epidermal desquamation

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7 January 2021

Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort

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7 January 2021

The natural course of atopic dermatitis from birth to age 7 years and the association with asthma.

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7 January 2021

Fleshing out filaggrin phenotypes

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7 January 2021

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

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7 January 2021

Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis.

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7 January 2021

Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier

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7 January 2021

Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery.

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7 January 2021

Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities

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7 January 2021

Three-dimensional analyses of individual corneocytes with atomic force microscope: morphological changes related to age, location and to the pathologic skin conditions

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7 January 2021

Association of SPINK5 gene polymorphisms with atopic dermatitis in the Japanese population

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7 January 2021

Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases

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7 January 2021

Loss-of-Function Mutations in the Filaggrin Gene Lead to Reduced Level of Natural Moisturizing Factor in the Stratum Corneum

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7 January 2021

A method for the measurement and evaluation of irritants on human skin

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7 January 2021

Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Factors associated with the development of peanut allergy in childhood

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7 January 2021

Membrane coating granules: The fate of the discharged lamellae

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7 January 2021

Formation of horny cells: the fate of cell organelles and differentiation products in ruminal epithelium

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7 January 2021

Calcium and potassium are important regulators of barrier homeostasis in murine epidermis

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7 January 2021

Skin thickness of Korean adults

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

A major susceptibility locus for atopic dermatitis maps to chromosome 3q21.

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Atopic dermatitis: new insights and opportunities for therapeutic intervention

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Staphylococcus aureus in the lesions of atopic dermatitis

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification, in stratum corneum cell cohesion and desquamation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

LEKTI, a novel 15-domain type of human serine proteinase inhibitor

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Association between variants of mast cell chymase gene and serum IgE levels in eczema

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Acute barrier perturbation abolishes the Ca2+ and K+ gradients in murine epidermis: quantitative measurement using PIXE.

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Atopic eczema and the home environment

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Atopic eczema and domestic water hardness.

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Prevalence of hand eczema in an industrial city

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https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Microanalytical screening of all major stratum corneum lipids by sequential high-performance thin-layer chromatography

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Lamellar body secretory response to barrier disruption

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Selective obliteration of the epidermal calcium gradient leads to enhanced lamellar body secretion

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Proteolytic activity of Staphylococcus aureus strains isolated from the colonized skin of patients with acute-phase atopic dermatitis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Filaggrin mutations in children with severe atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The genetics of atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Prevalence of atopic dermatitis in Leicester: a study of methodology and examination of possible ethnic variation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Clinical Severity Correlates with Impaired Barrier in Filaggrin-Related Eczema

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Human defensins and cathelicidins in the skin: beyond direct antimicrobial properties

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Specific Filaggrin Mutations Cause Ichthyosis Vulgaris and Are Significantly Associated with Atopic Dermatitis in Japan

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Allergic hyperreactivity to microbial components: a trigger factor of "intrinsic" atopic dermatitis?

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Filaggrin in atopic dermatitis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Virulence factors of the coagulase-negative staphylococci

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Regional differences of cell sizes in the human stratum corneum. I

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The skin: an indispensable barrier

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Analysis of Lipid Composition of Isolated Human Sebaceous Gland Homogenates After Incubation with Cutaneous Bacteria. Thin-Layer Chromatography

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Trends in stratum corneum research and the management of dry skin conditions

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Factors affecting the rapid disappearance of bacteria placed on the normal skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Evidence for filaggrin as a component of the cell envelope of the newborn rat.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The acidic milieu of the horny layer: new findings on the physiology and pathophysiology of skin pH.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Filaggrin mutations confer susceptibility to atopic dermatitis but not to asthma

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Antimicrobial peptides and the skin immune defense system

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Decreased expression of filaggrin in atopic skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Heterozygous Null Alleles in Filaggrin Contribute to Clinical Dry Skin in Young Adults and the Elderly

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Identification of Late Differentiation Antigens of Human Cornified Epithelia, Expressed in Re-Organized Desmosomes and Bound to Cross-Linked Envelope

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Immunolocalization of stratum corneum chymotryptic enzyme in human skin and oral epithelium with monoclonal antibodies: evidence of a proteinase specifically expressed in keratinizing squamous epithelia

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The thickness of the skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Atopic dermatitis and the atopic march

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The spectrum of pathogenic mutations in SPINK5 in 19 families with Netherton syndrome: implications for mutation detection and first case of prenatal diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Characterization of a class of cationic proteins that specifically interact with intermediate filaments

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Two Common Loss-of-Function Mutations within the Filaggrin Gene Predispose for Early Onset of Atopic Dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The role of proteases in stratum corneum: involvement in stratum corneum desquamation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Hypothesis: from epidermal barrier dysfunction to atopic disorders

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Variability of enzyme markers during clinical regression of atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Changes in the reported prevalence of childhood eczema since the 1939-45 war

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

House dust mites on skin, clothes, and bedding of atopic dermatitis patients

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Chymase participates in chronic dermatitis by inducing eosinophil infiltration

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

A nonsynonymous substitution of cystatin A, a cysteine protease inhibitor of house dust mite protease, leads to decreased mRNA stability and shows a significant association with atopic dermatitis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Desmoplakin is essential in epidermal sheet formation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Changes in diapered and nondiapered infant skin over the first month of life

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Profiling of serine protease activities in human stratum corneum and detection of a stratum corneum tryptase-like enzyme

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Increased basal transepidermal water loss leads to elevation of some but not all stratum corneum serine proteases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Efficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The incidence of eczema in early childhood

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Gene polymorphism in Netherton and common atopic disease

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Stratum corneum thiol protease (SCTP): a novel cysteine protease of late epidermal differentiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The effect of washing on the thickness of the stratum corneum in normal and atopic individuals

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Is the prevalence of atopic dermatitis increasing?

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Barrier disruption increases gene expression of cytokines and the 55 kD TNF receptor in murine skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Allergens from Dermatophagoides mites with chymotryptic activity

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Number of cell layers of the stratum corneum in normal skin - relationship to the anatomical location on the body, age, sex and physical parameters

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Trends in the prevalence of atopic dermatitis in school children: longitudinal study in Osaka Prefecture, Japan, from 1985 to 1997.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021

Cystatin M/E expression is restricted to differentiated epidermal keratinocytes and sweat glands: a new skin-specific proteinase inhibitor that is a target for cross-linking by transglutaminase.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.133

7 January 2021