Receptor-mediated endocytosis in renal proximal tubule (Q37508760)

20 August 2017

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title

Receptor-mediated endocytosis in renal proximal tubule (English)

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20 August 2017

Erik Ilsø Christensen

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1

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PubMed ID

19499243

20 August 2017

Pierre J Verroust

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2

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PubMed ID

19499243

20 August 2017

Rikke Nielsen

series ordinal

3

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20 August 2017

5 June 2009

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20 August 2017

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20 August 2017

458

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20 August 2017

1039-1048

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20 August 2017

6

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https://scigraph.springernature.com/pub.10.1007/s00424-009-0685-8

20 August 2017

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12 December 2020

Defective brush-border expression of intrinsic factor-cobalamin receptor in canine inherited intestinal cobalamin malabsorption

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12 December 2020

Interactions of cubilin with megalin and the product of the amnionless gene (AMN): effect on its stability

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12 December 2020

The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

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12 December 2020

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states

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12 December 2020

An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3

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12 December 2020

Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.

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12 December 2020

Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules.

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12 December 2020

Role of megalin and cubilin in renal physiology and pathophysiology.

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12 December 2020

Disease-dependent mechanisms of albuminuria

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12 December 2020

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

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12 December 2020

Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP)

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12 December 2020

Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family

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12 December 2020

Megalin/gp330 mediates uptake of albumin in renal proximal tubule

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12 December 2020

Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule

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12 December 2020

The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region

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12 December 2020

Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport

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12 December 2020

Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins

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12 December 2020

Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats

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12 December 2020

Megalin and cubilin: multifunctional endocytic receptors

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12 December 2020

Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation

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12 December 2020

Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules

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12 December 2020

The CUB domain. A widespread module in developmentally regulated proteins

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12 December 2020

Cubilin and megalin co-localize in the neonatal inner ear.

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12 December 2020

Folding, calcium binding, and structural characterization of a concatemer of the first and second ligand-binding modules of the low-density lipoprotein receptor.

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12 December 2020

Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins

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12 December 2020

Independent two-photon measurements of albumin GSC give low values

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12 December 2020

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

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12 December 2020

Purification, properties, and immunochemical localization of a receptor for intrinsic factor-cobalamin complex in the rat kidney

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12 December 2020

Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia

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12 December 2020

BMP-binding modules in chordin: a model for signalling regulation in the extracellular space

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12 December 2020

Molecular Dissection of the Intrinsic Factor-Vitamin B12Receptor, Cubilin, Discloses Regions Important for Membrane Association and Ligand Binding

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12 December 2020

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

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12 December 2020

Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex

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12 December 2020

Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.

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12 December 2020

Megalin and nonmuscle myosin heavy chain IIA interact with the adaptor protein Disabled-2 in proximal tubule cells

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12 December 2020

Renal albumin absorption in physiology and pathology

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12 December 2020

In situ hybridization mapping of a 500-kDa calcium-sensing protein gene (LRP2) to human chromosome region 2q31-->q32.1 and porcine chromosome region 15q22-->q24

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12 December 2020

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

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12 December 2020

Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties

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12 December 2020

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

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12 December 2020

The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis

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12 December 2020

The Adaptor Protein ARH Escorts Megalin to and through Endosomes

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12 December 2020

Glomerular sieving coefficient of serum albumin in the rat: a two-photon microscopy study

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12 December 2020

Defective forebrain development in mice lacking gp330/megalin

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12 December 2020

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

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12 December 2020

Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo

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12 December 2020

Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly

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12 December 2020

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

1 reference

12 December 2020

Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1

1 reference

12 December 2020

Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique

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12 December 2020

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

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12 December 2020

Renal albumin handling: a look at the dark side of the filter

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12 December 2020

Diversity in rat tissue accumulation of vitamin B12 supports a distinct role for the kidney in vitamin B12 homeostasis.

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12 December 2020

Albumin absorption and catabolism by isolated perfused proximal convoluted tubules of the rabbit

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12 December 2020

Receptor-associated protein (RAP): a specialized chaperone for endocytic receptors

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12 December 2020

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

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12 December 2020

Identification of an apical sorting determinant in the cytoplasmic tail of megalin

1 reference

12 December 2020

Distribution of alpha-galactosidase A in normal human kidney and renal accumulation and distribution of recombinant alpha-galactosidase A in Fabry mice

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12 December 2020

Controversies in nephrology: renal albumin handling, facts, and artifacts!

1 reference

12 December 2020

Absorption of I-125-labeled homologous albumin by rat kidney proximal tubule cells. A study of microperfused single proximal tubules by electron microscopic autoradiography and histochemistry

1 reference

12 December 2020

Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein

1 reference

12 December 2020

Genetically heterogeneous selective intestinal malabsorption of vitamin B12: founder effects, consanguinity, and high clinical awareness explain aggregations in Scandinavia and the Middle East

1 reference

12 December 2020

Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin

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12 December 2020

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

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12 December 2020

Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor

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12 December 2020

Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria

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12 December 2020

Rapid membrane recycling in renal proximal tubule cells

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12 December 2020

Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin

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12 December 2020

Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo

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12 December 2020

Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.

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12 December 2020

Membrane receptors for endocytosis in the renal proximal tubule.

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12 December 2020

Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein

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12 December 2020

Evidence for an essential role of megalin in transepithelial transport of retinol

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12 December 2020

Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo.

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12 December 2020

Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney

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12 December 2020

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

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12 December 2020

The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

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12 December 2020

The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border

1 reference

12 December 2020

Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module

1 reference

12 December 2020

Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo

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12 December 2020

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)

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12 December 2020

The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain

1 reference

12 December 2020

Genetic evidence of an accessory activity required specifically for cubilin brush-border expression and intrinsic factor-cobalamin absorption

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12 December 2020

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis

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12 December 2020

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

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12 December 2020

Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

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12 December 2020

Identification of the second cluster of ligand-binding repeats in megalin as a site for receptor-ligand interactions

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12 December 2020

Identification and characterization of two distinct ligand binding regions of cubilin

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12 December 2020

10.1007/S00424-009-0685-8

Identifiers

DOI

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20 August 2017

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PubMed ID

19499243