UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation. (Q37519690)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24395786%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation (English)

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4 March 2020

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4 March 2020

Francesco De Leonardis

3

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Eleonora Paradies

11

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4 March 2020

Pasquale Scarcia

12

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4 March 2020

Frédéric Bouillaud

14

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4 March 2020

Giuseppe Fiermonte

15

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Francesco Massimo Lasorsa

4 March 2020

4

object named as

Francesco M Lasorsa

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4 March 2020

9

Luigi Palmieri

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4 March 2020

5

Alessandra Castegna

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4 March 2020

author name string

Giovanni Parisi

2

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4 March 2020

Daniela Amorese

6

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4 March 2020

Raffaele Marmo

7

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4 March 2020

Valeria M Calcagnile

8

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4 March 2020

Daniel Ricquier

10

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4 March 2020

Ferdinando Palmieri

13

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4 March 2020

language of work or name

English

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publication date

6 January 2014

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Proceedings of the National Academy of Sciences of the United States of America

4 March 2020

published in

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4 March 2020

volume

111

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4 March 2020

issue

3

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4 March 2020

page(s)

960-965

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

4 March 2020

cites work

1 reference

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Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin

23 August 2017

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Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondria

23 August 2017

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UCP2 inhibits ROS-mediated apoptosis in A549 under hypoxic conditions

23 August 2017

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Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

23 August 2017

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Reductive carboxylation supports growth in tumour cells with defective mitochondria.

23 August 2017

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UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

23 August 2017

1 reference

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Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin

23 August 2017

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Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

23 August 2017

1 reference

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Uncoupling protein-2 and the potential link between metabolism and longevity.

23 August 2017

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Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion

23 August 2017

1 reference

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The mechanism of transport by mitochondrial carriers based on analysis of symmetry

23 August 2017

1 reference

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The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation

23 August 2017

1 reference

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

23 August 2017

1 reference

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Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia

23 August 2017

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

23 August 2017

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Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.

23 August 2017

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The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms

23 August 2017

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The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions.

23 August 2017

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Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

23 August 2017

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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

23 August 2017

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Uncoupling protein 2 from carp and zebrafish, ectothermic vertebrates

23 August 2017

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The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans

23 August 2017

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

23 August 2017

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

23 August 2017

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Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism

23 August 2017

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Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function.

6 September 2017

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Mitochondrial uncoupling protein 2 in pancreatic β-cells.

6 September 2017

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Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action

6 September 2017

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Glutamine stimulates translation of uncoupling protein 2mRNA.

6 September 2017

1 reference

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Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives

14 September 2017

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Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction

14 September 2017

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Metformin induces oxidative stress in white adipocytes and raises uncoupling protein 2 levels

28 September 2017

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Reconstitution of recombinant uncoupling proteins: UCP1, -2, and -3 have similar affinities for ATP and are unaffected by coenzyme Q10.

25 June 2018

1 reference

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Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria

25 June 2018

1 reference

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Tissue-dependent upregulation of rat uncoupling protein-2 expression in response to fasting or cold.

25 June 2018

1 reference

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Abundant bacterial expression and reconstitution of an intrinsic membrane-transport protein from bovine mitochondria

25 June 2018

1 reference

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Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization.

25 June 2018

1 reference

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Requirement of PPARalpha in maintaining phospholipid and triacylglycerol homeostasis during energy deprivation.

2 September 2018

1 reference

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The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in DeltapH formation across peroxisomal membranes

2 September 2018

1 reference

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THE EFFECTS OF ADENINE NUCLEOTIDES ON PYRUVATE METABOLISM IN RAT LIVER

2 September 2018

1 reference

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Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903233

Mechanism for peroxisome proliferator-activated receptor-alpha activator-induced up-regulation of UCP2 mRNA in rodent hepatocytes

2 September 2018

1 reference

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Inhibition of Respiration under the Control of Azide Uptake by Mitochondria

2 September 2018

1 reference

12 December 2020

Transport of anions and protons by the mitochondrial uncoupling protein and its regulation by nucleotides and fatty acids. A new look at old hypotheses

1 reference

12 December 2020

Mitochondrial metabolite carrier proteins: purification, reconstitution, and transport studies

1 reference

12 December 2020

Transformed but not normal hepatocytes express UCP2

1 reference

12 December 2020

Transport function and regulation of mitochondrial uncoupling proteins 2 and 3

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1317400111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24395786%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

1 reference

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4 March 2020

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